170707-53-6

Upstream product

• 1825-61-2 Trimethylmethoxysilane 
• 136314-66-4 methyl (3S,4E)-3-(dimethylphenylsilyl)-4-hexenoate 
• 170707-52-5 (2S,4S,5R)-5-(2,5-dimethoxy-3-nitrophenyl)-2,5-dimethoxy-4-methylpentanal 
• 170707-49-0 [(2R,3S,5S,6R)-2-Benzyloxy-6-(2,5-dimethoxy-3-nitro-phenyl)-3,6-dimethoxy-5-methyl-hexyloxy]-tert-butyl-dimethyl-silane 
• 170707-48-9 (2R,3S,5S,6R)-2-Benzyloxy-1-(tert-butyl-dimethyl-silanyloxy)-6-(2,5-dimethoxy-3-nitro-phenyl)-6-methoxy-5-methyl-hexan-3-ol 
• 170707-50-3 (2R,3S,5S,6R)-2-Benzyloxy-6-(2,5-dimethoxy-3-nitro-phenyl)-3,6-dimethoxy-5-methyl-hexan-1-ol 
• 170901-52-7 (2R,3S,5S,6R)-2-Benzyloxy-6-(2,5-dimethoxy-3-nitro-phenyl)-6-methoxy-5-methyl-hexane-1,3-diol 

Downstream Products

• 649566-97-2 5-(tert-butyl-dimethyl-silanyloxy)-13-(2,5-dimethoxy-3-nitro-phenyl)-4,9,10,13-tetramethoxy-6,8,12-trimethyl-trideca-2,6-dienoic acid methyl ester 
• 649566-98-3 5-(tert-butyl-dimethyl-silanyloxy)-13-(2,5-dimethoxy-3-nitro-phenyl)-4,9,10,13-tetramethoxy-6,8,12-trimethyl-trideca-2,6-dien-1-ol 
• 649566-94-9 5-(tert-butyl-dimethyl-silanyloxy)-13-(2,5-dimethoxy-3-nitro-phenyl)-4,9,10,13-tetramethoxy-6,8,12-trimethyl-trideca-2,6-dienal 
• 649566-93-8 tert-butyl-[9-(2,5-dimethoxy-3-nitro-phenyl)-5,6,9-trimethoxy-1-(1-methoxy-allyl)-2,4,8-trimethyl-non-2-enyloxy]-dimethyl-silane 
• 649566-92-7 3-(tert-butyl-dimethyl-silanyl)-11-(2,5-dimethoxy-3-nitro-phenyl)-2,7,8,11-tetramethoxy-4,6,10-trimethyl-undec-4-enal 
• 649566-96-1 12-(2,5-dimethoxy-3-nitro-phenyl)-3,8,9,12-tetramethoxy-5,7,11-trimethyl-dodeca-1,5-diene-4-ol 
• 170707-55-8 (E)-(4S,5R,6S,8S,9R)-9-(2,5-Dimethoxy-3-nitro-phenyl)-5,6,9-trimethoxy-2,4,8-trimethyl-non-2-enoic acid ethyl ester 
• 170707-57-0 (E)-(4S,5R,6S,8S,9R)-9-(2,5-Dimethoxy-3-nitro-phenyl)-5,6,9-trimethoxy-2,4,8-trimethyl-non-2-enal 
• 170707-56-9 (E)-(4S,5R,6S,8S,9R)-9-(2,5-Dimethoxy-3-nitro-phenyl)-5,6,9-trimethoxy-2,4,8-trimethyl-non-2-en-1-ol 
• 170707-54-7 (2R,3R,4S,6S,7R)-7-(2,5-dimethoxy-3-nitrophenyl)-3,4,7-trimethoxy-2,6-dimethylheptanal 
• 145798-97-6 15-(3-amino-2,5-dimethoxy-phenyl)-7-(tert-butyl-dimethyl-silanyloxy)-6,11,12,15-tetramethoxy-2,8,10,14-tetramethyl-pentadeca-2,4,8-trienoic acid 
• 70563-58-5 herbimycin A 

Relevant academic research and scientific papers

Total Synthesis of Herbimycin A

(Equation presented) Herbimycin A (HA) belongs to a class of antibiotics known as the benzoquinoid ansamycins. Members of this class have shown promising biological activity as Hsp90 inhibitors. An enantioselective synthesis of HA is described, employing

Chiral crotylsilane-based approach to benzoquinoid ansamycins: Total synthesis of (+)-macbecin I

A highly convergent total synthesis of the antitumor antibiotic (+)- macbecin I (1) has been achieved through the homologation of the aldehyde 3 (C5-C21 aromatic fragment) to the E, Z-dienoate 2 by employing a sequential olefination strategy. Subsequent m