17076-74-3

Upstream product

• 22528-34-3 3-amino-4'-nitrodiphenyl ether 
• 544-92-3 copper(I) cyanide 
• 873-62-1 m-cyanophenol 
• 350-46-9 4-Fluoronitrobenzene 
• 22483-34-7 acetic acid-[3-(4-nitro-phenoxy)-anilide] 
• 76506-19-9 Potassium; 3-acetylamino-phenolate 
• 586-78-7 para-nitrophenyl bromide 

Downstream Products

• 305801-18-7 4-(3-cyanophenoxy)aniline 
• 30202-98-3 4-(4-Amino-phenoxy)-benzylamin 

Relevant academic research and scientific papers

3,4-DISUBSTITUTED MALEIMIDES FOR USE AS VASCULAR DAMAGING AGENTS

This invention relates to novel compounds of Formula (I) for use as vascular damaging agents: Formula (I) wherein Rl, R7, R8, R9, ARI, AR2, AR3, p, q and r are as described in the specification. The invention also relates to methods for preparing compounds of Formula (I), to their use as medicaments (including methods for the treatment of angiogenesis or disease states associated with angiogenesis) and to pharmaceutical compositions containing compounds of Formula (I).

ENTRY INHIBITORS OF THE HIV VIRUS

The present invention relates to small molecules as entry inhibitors of the HIV virus, processes for their preparation as well as pharmaceutical compositions, their use as medicines, and diagnostic kits comprising them. The present invention also concerns combinations of the present entry inhibitors with other anti-retroviral agents. It further relates to their use in assays as reference compounds or as reagents. The compounds of the present invention are useful for preventing or treating infection by HIV and for treating AIDS. The compounds of formula (I) have the following structure: (I).