1708-73-2

Basic information

• Product Name: [(chloromethyl)sulfanyl]ethane
• Synonyms: Chloromethyl ethyl sulfide; Ethane, ((chloromethyl)thio)-; Sulfide, chloromethyl ethyl
• CAS NO: 1708-73-2
• Molecular Formula: C₃H₇ClS
• Molecular Weight: 110.6057
• Mol File: 1708-73-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 105.1°C at 760 mmHg
• Flash Point: 29.4°C
• Density: 1.069g/cm³
• Vapor Pressure: 34.8mmHg at 25°C
• Refractive Index: 1.468
• Storage Temp.: -20°C Freezer
• Solubility: Dichloromethane; Ethyl Acetate; Methanol
• CAS DataBase Reference: [(chloromethyl)sulfanyl]ethane(CAS DataBase Reference)
• NIST Chemistry Reference: [(chloromethyl)sulfanyl]ethane(1708-73-2)
• EPA Substance Registry System: [(chloromethyl)sulfanyl]ethane(1708-73-2)

Safety Data

• Hazardous Substances Data: 1708-73-2(Hazardous Substances Data)

Usage

Uses

[(Chloromethyl)thio]-ethane is an intermediate in the synthesis of Phorate Oxon Sulfone (P353515). Phorate Oxon Sulfone is a major metabolite of Phorate (P353500), an inhibitor of acetylcholinesterase and pseudocholinesterase.

Upstream product

• 110-88-3 1,3,5-Trioxan 
• 75-08-1 ethanethiol 
• 1496-75-9 Ethanesulfenyl chloride 
• 291-21-4 [1,3,5]trithiane 
• 56-23-5 tetrachloromethane 
• 50-00-0 formaldehyd 
• 186581-53-3 diazomethane 
• 60-29-7 diethyl ether 

Downstream Products

• 50376-21-1 formaldehyde-(ethyl-benzyl-dithioacetal) 
• 4396-19-4 bis(ethylthio)methane 
• 54091-78-0 diethyl ((ethylthio)methyl)phosphonate 
• 20280-43-7 1-Ethylsulfanylmethyl-aziridine 
• 7647-01-0 hydrogenchloride 
• 50-00-0 formaldehyd 
• 91694-20-1 Cyclohexyl-ethyl-thiocarbamic acid S-ethylsulfanylmethyl ester 
• 18673-13-7 3-ethylsulfanylpropionic acid methyl ester 
• 854751-60-3 acetic acid-[4-(ethylsulfanyl-methylsulfanyl)-anilide] 
• 119015-51-9 1-(ethylsulfanyl-methoxy)-2,4-dichloro-benzene 
• 98995-44-9 ethylsulfanyl-(4-chloro-phenylsulfanyl)-methane 
• 298-02-2 Phorate 
• 98995-29-0 ethylsulfanyl-(4-chloro-phenoxy)-methane 
• 1728-94-5 Chloromethyl ethyl sulfone 

Relevant articles and documents

Regiochemistry and reactivity in the chlorination of sulfides

Huheey's original method for the calculation of substituent electronegativities is modified so that isomeric groups have different electronegativities.The modified form of Huheey's method is then employed to show that our previously published method for anticipating regiochemistry in asymmetric sulfide chlorination, i.e., ΔXP calculations for the α and α' substituents in the sulfide substrates, is successful in all fifty known cases.A new reactivity function (RP) is defined, for the sulfenium ion intermediates, which permits one to anticipate when substrates become inert to chlorine in exhaustive chlorinations conducted in aprotic media.