Welcome to LookChem.com Sign In|Join Free

CAS

  • or

170842-80-5

Post Buying Request

170842-80-5 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

170842-80-5 Usage

General Description

3-Benzyl-piperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester is a chemical compound that belongs to the class of piperidine derivatives. It is commonly used as an intermediate in the synthesis of pharmaceuticals and organic compounds. 3-BENZYL-PIPERIDINE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-ETHYL ESTER has potential applications in medicinal chemistry and drug discovery due to its unique structure and functional groups. It can be used as a building block for the synthesis of bioactive molecules and has the potential to exhibit pharmacological activity. Additionally, it may have uses in the field of organic synthesis and chemical research.

Check Digit Verification of cas no

The CAS Registry Mumber 170842-80-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,0,8,4 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 170842-80:
(8*1)+(7*7)+(6*0)+(5*8)+(4*4)+(3*2)+(2*8)+(1*0)=135
135 % 10 = 5
So 170842-80-5 is a valid CAS Registry Number.

170842-80-5 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Alfa Aesar

  • (H33958)  Ethyl 1-Boc-3-benzylpiperidine-3-carboxylate, 95%   

  • 170842-80-5

  • 250mg

  • 576.0CNY

  • Detail
  • Alfa Aesar

  • (H33958)  Ethyl 1-Boc-3-benzylpiperidine-3-carboxylate, 95%   

  • 170842-80-5

  • 1g

  • 1597.0CNY

  • Detail

170842-80-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-O-tert-butyl 3-O-ethyl 3-benzylpiperidine-1,3-dicarboxylate

1.2 Other means of identification

Product number -
Other names 3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:170842-80-5 SDS

170842-80-5Synthetic route

ethyl N-(t-butyloxycarbonyl)nipecotate
148672-74-6, 130250-54-3

ethyl N-(t-butyloxycarbonyl)nipecotate

benzyl bromide
100-39-0

benzyl bromide

3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester
170842-80-5

3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester

Conditions
ConditionsYield
With lithium hexamethyldisilazane 1.) THF, -78 deg C, 2.) THF, from -78 deg C to 0 deg C; Multistep reaction;
With hydrogenchloride; sodium hexamethyldisilazane In tetrahydrofuran; ethyl acetate; toluene
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester
170842-80-5

3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: CH2Cl2
2: 1.) lithium bis(trimethylsilyl)amide / 1.) THF, -78 deg C, 2.) THF, from -78 deg C to 0 deg C
View Scheme
Ethyl nipecotate
71962-74-8

Ethyl nipecotate

3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester
170842-80-5

3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: CH2Cl2
2: 1.) lithium bis(trimethylsilyl)amide / 1.) THF, -78 deg C, 2.) THF, from -78 deg C to 0 deg C
View Scheme
ethyl N-(t-butyloxycarbonyl)nipecotate
148672-74-6, 130250-54-3

ethyl N-(t-butyloxycarbonyl)nipecotate

benzyl bromide
100-39-0

benzyl bromide

lithium diisopropyl amide
4111-54-0

lithium diisopropyl amide

3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester
170842-80-5

3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester

Conditions
ConditionsYield
In tetrahydrofuran
(42/58) MeCN

(42/58) MeCN

(42/58→62/38) MeCN

(42/58→62/38) MeCN

(62/38) MeCN

(62/38) MeCN

S-3-Carbethoxy-3-benzyl-2-hydroxy-N-Boc-piperidine

S-3-Carbethoxy-3-benzyl-2-hydroxy-N-Boc-piperidine

phosphoric acid
86119-84-8, 7664-38-2

phosphoric acid

boron trifluoride
7637-07-2

boron trifluoride

tert-butyl nitrosoformate
121893-20-7

tert-butyl nitrosoformate

3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester
170842-80-5

3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester

Conditions
ConditionsYield
With triethylsilane; trifluoroborane diethyl ether In dichloromethane
3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester
170842-80-5

3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester

3-Benzyl-piperidine-3-carboxylic acid ethyl ester
170844-89-0

3-Benzyl-piperidine-3-carboxylic acid ethyl ester

Conditions
ConditionsYield
With hydrogenchloride In ethyl acetate
3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester
170842-80-5

3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester

(S)-1-[(R)-2-Amino-3-(1H-indol-3-yl)-propionyl]-3-benzyl-piperidine-3-carboxylic acid ethyl ester; hydrochloride

(S)-1-[(R)-2-Amino-3-(1H-indol-3-yl)-propionyl]-3-benzyl-piperidine-3-carboxylic acid ethyl ester; hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: HCl / ethyl acetate
3: HOBt, EDC / CH2Cl2
4: HCl / ethyl acetate
View Scheme
3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester
170842-80-5

3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester

L-163,540*HCl*H2O

L-163,540*HCl*H2O

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: HCl / ethyl acetate
3: HOBt, EDC / CH2Cl2
4: HCl / ethyl acetate
5: HOBt, EDC / CH2Cl2
6: HCl / ethyl acetate
View Scheme
3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester
170842-80-5

3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester

(S)-3-carbethoxy-3-benzylpiperidine
170844-45-8

(S)-3-carbethoxy-3-benzylpiperidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: HCl / ethyl acetate
View Scheme
3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester
170842-80-5

3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester

(S)-3-Benzyl-1-[(R)-2-tert-butoxycarbonylamino-3-(1H-indol-3-yl)-propionyl]-piperidine-3-carboxylic acid ethyl ester
170844-47-0

(S)-3-Benzyl-1-[(R)-2-tert-butoxycarbonylamino-3-(1H-indol-3-yl)-propionyl]-piperidine-3-carboxylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: HCl / ethyl acetate
3: HOBt, EDC / CH2Cl2
View Scheme
3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester
170842-80-5

3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester

(S)-3-Benzyl-1-[(R)-2-(2-tert-butoxycarbonylamino-2-methyl-propionylamino)-3-(1H-indol-3-yl)-propionyl]-piperidine-3-carboxylic acid ethyl ester
170842-83-8

(S)-3-Benzyl-1-[(R)-2-(2-tert-butoxycarbonylamino-2-methyl-propionylamino)-3-(1H-indol-3-yl)-propionyl]-piperidine-3-carboxylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: HCl / ethyl acetate
3: HOBt, EDC / CH2Cl2
4: HCl / ethyl acetate
5: HOBt, EDC / CH2Cl2
View Scheme
3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester
170842-80-5

3-Benzylpiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester

(+/-)-N-(t-butoxycarbonyl)-3-(hydroxymethyl)-3-(phenylmethyl)-piperidine
170838-92-3

(+/-)-N-(t-butoxycarbonyl)-3-(hydroxymethyl)-3-(phenylmethyl)-piperidine

Conditions
ConditionsYield
With hydrogenchloride; diisobutylaluminium hydride In ethyl acetate; toluene

170842-80-5Relevant articles and documents

Compound with growth hormone releasing properties

-

, (2008/06/13)

The present invention describes a new compound, 2-Amino-N-[(1R)-2-[(3R)-3-benzyl-3-(N,N′,N′-trimethylhydrazinocarbonyl)piperidin-1-y]-1-(1H-indol-3-ylmethyl)-2-oxoethyl]-2-methylpropionamide, having the formula: and pharmaceutically acceptable salts thereof, compositions containing them, and their use for treating medical disorders resulting from a deficiency in growth hormone.

Process for the preparation of (S)-3-carbethoxy-3-benzylpiperidine

-

, (2008/06/13)

The present invention is concerned with a novel process for the preparation of a compound of the formula: STR1 This compound is useful as an intermediate in the synthesis of compounds which possess pharmacological activity.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 170842-80-5