1709-39-3

Basic information

• Product Name: 4-AMINO-N,N-DIETHYL-BENZENESULFONAMIDE
• Synonyms: TIMTEC-BB SBB000688;OTAVA-BB BB7210740770;4-amino-n,n-diethyl-benzenesulfonamid;n(sup1),n(sup1)-diethylsulfanilamide;N^l,n^l-diethylsulfanilamide;4-AMINO-N,N-DIETHYL-BENZENESULFONAMIDE;AKOS BBS-00000287;AKOS BBB/020
• CAS NO: 1709-39-3
• Molecular Formula: C₁₀H₁₆N₂O₂S
• Molecular Weight: 228.31
• Mol File: 1709-39-3.mol
• Article Data: 11

Chemical Properties

• Melting Point: 105-106 °C
• Boiling Point: 375.9 °C at 760 mmHg
• Flash Point: 181.1 °C
• Appearance: /
• Density: 1.199 g/cm³
• Vapor Pressure: 7.54E-06mmHg at 25°C
• Refractive Index: 1.56
• Storage Temp.: 2-8°C
• PKA: 2.14±0.10(Predicted)
• CAS DataBase Reference: 4-AMINO-N,N-DIETHYL-BENZENESULFONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-N,N-DIETHYL-BENZENESULFONAMIDE(1709-39-3)
• EPA Substance Registry System: 4-AMINO-N,N-DIETHYL-BENZENESULFONAMIDE(1709-39-3)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 1709-39-3(Hazardous Substances Data)

Usage

General Description

4-AMINO-N,N-DIETHYL-BENZENESULFONAMIDE is a chemical compound with the molecular formula C10H16N2O2S. It is a sulfonamide derivative, which is a class of drugs commonly used as antibiotics and diuretics. This specific compound is used as an intermediate in the synthesis of pharmaceuticals and may also have applications in organic synthesis. It is a white to off-white solid with a faint odor, and its chemical structure includes an amino group, a diethyl group, and a benzene ring with a sulfonamide functional group attached. 4-AMINO-N,N-DIETHYL-BENZENESULFONAMIDE should be handled and stored according to proper safety protocols due to its potential as a hazardous material.

InChI:InChI=1/C10H16N2O2S/c1-3-12(4-2)15(13,14)10-7-5-9(11)6-8-10/h5-8H,3-4,11H2,1-2H3

Upstream product

• 10026-13-8 phosphorus pentachloride 
• 109-89-7 diethylamine 
• 121-57-3 4-aminobenzene sulfonic acid 
• 98-74-8 4-Nitrobenzenesulfonyl chloride 
• 121-60-8 p-acetylaminobenzenesulfonyl chloride 
• 89840-82-4 N,N-Diethyl-4-nitro-benzenesulfonamide 
• 107145-69-7 N-dichlorophosphoryl-sulfanilyl chloride 
• 2080-32-2 N⁴-acetyl-N¹-diethylsulfanilamide 

Downstream Products

• 315672-03-8 N-(N-acetyl-sulfanilyl)-sulfanilic acid diethylamide 
• 61679-66-1 (Z)-2-Cyano-3-(4-diethylsulfamoyl-phenylamino)-acrylic acid ethyl ester 
• 94243-30-8 4-(Cyanomethyl-amino)-N,N-diethyl-benzenesulfonamide 
• 96722-51-9 C₁₄H₂₀ClN₃O₄S 
• 42556-43-4 4-((E)-3,7-Dimethyl-octa-2,6-dienylamino)-N,N-diethyl-benzenesulfonamide 
• 873971-03-0 N-sulfanilyl-sulfanilic acid diethylamide 
• 99841-31-3 C₁₁H₁₄N₂O₂S₂ 
• 1383478-95-2 C₂₉H₃₅N₃O₃S₂ 
• 1366000-26-1 N-(4-diethylsulfamoyl-phenyl)-2-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrrolo[3,2-d]pyrimidin-5-yl)-acetamide 
• 1094225-40-7 N,N-diethyl-4-methylaminobenzenesulfonamide 
• 383388-43-0 N,N-diethyl-1-methyl-1H-indole-5-sulfonamide 
• 1352622-17-3 C₁₉H₂₃Cl₃N₂O₅S₂ 

Relevant articles and documents

Optimization of a urea-containing series of nicotinamide phosphoribosyltransferase (NAMPT) activators

NAD+ is a crucial cellular factor that plays multifaceted roles in wide ranging biological processes. Low levels of NAD+ have been linked to numerous diseases including metabolic disorders, cardiovascular disease, neurodegeneration,

Optimization of norbornyl-based carbocyclic nucleoside analogs as cyclin-dependent kinase 2 inhibitors

We report on the discovery of norbornyl moiety as a novel structural motif for cyclin-dependent kinase 2 (CDK2) inhibitors which was identified by screening a carbocyclic nucleoside analogue library. Three micromolar hits were expanded by the use of medic

A selective, tin-free radical mediated synthesis of indoles based on a sulfonate template

A synthesis of indoles based on a vinyl sulfonate template is described. The approach employs a sulfonate group which plays three discrete roles in the synthetic sequence. Firstly the highly electron-withdrawing sulfonate group behaves as an activating group for a 1,4-addition of an aniline to the unsaturated system. Secondly, the electron-withdrawing nature of the same group also allows it to behave as a radical stabilising group which facilitates radical cyclisation to an aromatic ring to yield a transient indoline. Finally, the pendant sulfonate group behaves as a leaving group to yield the indole.