170984-72-2 Usage
Uses
Used in Neuroscience Research:
EGLU is used as a research tool for studying the role of group II mGluRs in various neurological processes and disorders. It helps researchers understand the mechanisms underlying synaptic plasticity, learning, and memory, as well as the pathophysiology of neurodegenerative diseases and psychiatric disorders.
Used in Drug Abuse Treatment:
EGLU is used as an acupuncture inhibitor for methamphetamine-induced behaviors. It helps in reducing the rewarding effects of methamphetamine, which can contribute to the development of addiction. By inhibiting the activity of group II mGluRs, EGLU can potentially reduce the cravings and relapse associated with methamphetamine abuse.
Used in Neuroprotection:
EGLU is used for the inhibition of dopamine release and hyperthermia in the nucleus accumbens. This can be beneficial in protecting neurons from damage caused by excessive dopamine release and high body temperature, which are common in conditions such as Parkinson's disease and neurodegenerative disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 170984-72-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,0,9,8 and 4 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 170984-72:
(8*1)+(7*7)+(6*0)+(5*9)+(4*8)+(3*4)+(2*7)+(1*2)=162
162 % 10 = 2
So 170984-72-2 is a valid CAS Registry Number.
170984-72-2Relevant academic research and scientific papers
Asymmetric Strecker reaction of γ-keto acids. Facile entry to α-substituted and α,γ-disubstituted glutamic acids
Tang, Guozhi,Tian, Hongqi,Ma, Dawei
, p. 10547 - 10552 (2007/10/03)
The Strecker reaction of γ-keto acid derived sodium salts with (S)-phenylglycinol followed by treatment of the resultant α-amino nitriles with methanolic HCl and heating at 200°C give bicyclic lactones 11 and 12. Hydrolysis and subsequent debenzylation of
Enantioselective syntheses of α-substituted glutamic acids and α,γ-disubstituted glutamic acids by an asymmetric Strecker reaction
Ma, Dawei,Tang, Guozhi,Tian, Hongqi,Zou, Guixiang
, p. 5753 - 5756 (2007/10/03)
The Strecker reaction of the product from the treatment of the sodium salt of γ-keto acids with (S)-phenylglycinol followed by heating the products to 200 °C gives the bicyclic lactones 9 and 10. Alkylation of 9 provides 11 and 12. Both 9b and 11a are con
