17100-58-2

Usage

Uses

Used in Organic Synthesis:
(4-bromo-2-methylphenyl)methanol is used as an intermediate in the synthesis of various organic compounds. Its unique structure allows for further functionalization and modification, making it a valuable building block in the creation of complex molecules.
Used in Pharmacology:
In the field of pharmacology, (4-bromo-2-methylphenyl)methanol is used as a starting material for the development of new pharmaceutical agents. Its structural features can be exploited to design drugs with specific therapeutic properties, potentially leading to the discovery of novel treatments for various medical conditions.
Used in Chemical Research:
(4-bromo-2-methylphenyl)methanol is employed as a research compound in academic and industrial laboratories. Its reactivity and structural characteristics make it an interesting subject for studies in organic chemistry, providing insights into reaction mechanisms and the properties of related compounds.

Upstream product

• 24078-12-4 4-bromo-2-methylbenzaldehyde 
• 99548-55-7 4-bromo-2-methyl-benzoic acid methyl ester 
• 68837-59-2 4-bromo-2-methylbenzoic acid 

Downstream Products

• 24078-15-7 4-bromo-1-(chloromethyl)-2-methylbenzene 
• 24078-12-4 4-bromo-2-methylbenzaldehyde 
• 24078-25-9 4-hydroxymethyl-3-methylbenzoic acid methyl ester 
• 345965-75-5 (4-bromo-2-methyl-benzyloxy)-trimethylsilane 
• 156001-49-9 4-bromo-2-methylbenzyl bromide 
• 91587-35-8 4-(1-hydroxy-2,2,6-trimethylcyclohexyl)-2-methylbenzaldehyde 
• 91587-27-8 2-(4-bromo-2-methylphenyl)-1,3-dioxolane 
• 218594-34-4 (4-bromo-2-methylphenyl)methoxy-tert-butyldiphenylsilane 

Relevant academic research and scientific papers

COMPOSITION AND METHODS OF USE OF TETRAHYDROISOQUINOLINE SMALL MOLECULES TO BIND AND MODULATE PCSK9 PROTEIN ACTIVITY

This invention is related to the field of PCSK9 biology and the composition and methods of use of small organic compounds as ligands for modulation of PCSK9 biological activity. In particular, the invention provides compositions of small organic compounds

IMMUNE ADJUSTMENT COMPOUND, USE THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

The present invention provides a compound represented by formula I, wherein R is a halogen element or a C1-C6 alkyl group. The compound has S1 P1 receptor agonist activity and selective specificity and has obviously-shortened half-life in-vivo, and therefore the compound is a high-quality second-generation S1P1 receptor agonist. The present invention also provides a use of the compound in preparing medicine for treating diseases or symptoms mediated by an S1P1 receptor, a pharmaceutical composition comprising the compound, and uses of the compound and the pharmaceutical composition in treating diseases or symptoms mediated by the S1 P1 receptor.

SPIROCYCLIC COMPOUNDS AS TRYPTOPHAN HYDROXYLASE INHIBITORS

The present invention is directed to spirocyclic compounds which are inhibitors of tryptophan hydroxylase (TPH), particularly isoform 1 (TPH1), that are useful in the treatment of diseases or disorders associated with peripheral serotonin including, for example, gastrointestinal, cardiovascular, pulmonary, inflammatory, metabolic, and low bone mass diseases, as well as serotonin syndrome, and cancer.

PYRROLIDINE GPR40 MODULATORS

The present invention provides compounds of Formula (I): or a stereoisomer, a tautomer, a pharmaceutically acceptable salt, a polymorph, or a solvate thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.

4-{4-[(1 E)-4-(2,9-DIAZASPIRO[5.5]UNDEC-2-YL)BUT-1 -EN-1 -YL]-2-METHYLBENZYL}-5-(PROPAN-2-YL)-1 H-PYRAZOL-3-YL BETA-D- GLUCOPYRANOSIDE ACETATE

The present invention provides a compound of Formula I or hydrate thereof, useful for the treatment of diabetes.

SERINE/THREONINE KINASE INHIBITORS

Compounds having the formula I wherein R1, R2, R3, R4, R5, Ra, Rb, Rc, Rd, Re, n, r, s and t are as defined herein and which compounds are inhibitors of PAK1. Also disclosed are compositions and methods for treating cancer and hyperproliferative disorders.

Modulators of methyl modifying enzymes, compositions and uses thereof

Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.

FUSED TRICYCLIC AMIDE COMPOUNDS AS MULTIPLE KINASE INHIBITORS

Provided are fused tricyclic amide compounds, pharmaceutical compositions comprising at least one such fused tricyclic compound, processes for the preparation thereof, and the use thereof in therapy. Disclosed herein are certain tricyclic amide compounds that can be useful for inhibiting multiple (specifically BRAF and/or EGFR-T790M) kinases and for treating disorders mediated thereby.

PAR2 RECEPTOR ANTAGONISTS

Compounds of formula (I) or pharmaceutically acceptable salts, solvates or hydrates thereof wherein P, Q, X, Y, R1, R2, R3, R10, R11, and R12 are as defined in the claims, and the use those compounds in medicine.

RECEPTOR ANTAGONISTS

N-(4-carbamimidoylphenyl)-amide derivatives having utility in therapy as PAR2 receptor antagonists.