171009-36-2Relevant academic research and scientific papers
Synthetic studies towards the benzophenone precursor for balanol
Patil, Mahesh L.,Deshpande, Vishnu H.,Ramlingam,Borate, Hanumant B.
, p. 1869 - 1873 (2007/10/03)
Synthesis of 4-carboxy-2,6-dimethoxyphenyl 2′-carboxy-6′- methoxyphenyl ketone, an important precursor for balanol's benzophenone portion, has been achieved via a short and efficient route in three steps using ortho-lithiation as the key step. In another
Total synthesis of balanol: a potent protein kinase C inhibitor of fungal origin
Adams, C. P.,Fairway, S. M.,Hardy, C. J.,Hibbs, D. E.,Hursthouse, M. B.,et al.
, p. 2355 - 2362 (2007/10/02)
The total synthesis of the fungal metabolite balanol, a potent inhibitor of protein kinase C, is described.The synthesis includes a novel synthesis of 3-amino-4-hydroxyazepanes via a directed ring expansion of 3-bromopiperidin-4-ones.
