171056-23-8

Basic information

• Product Name: pentyl (2S)-2-hydroxypropanoate
• Synonyms: Pentyl (2S)-2-hydroxypropanoate; propanoic acid, 2-hydroxy-, pentyl ester, (2S)-
• CAS NO: 171056-23-8
• Molecular Formula: C₈H₁₆O₃
• Molecular Weight: 160.21
• Mol File: 171056-23-8.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 204.6°C at 760 mmHg
• Flash Point: 79.2°C
• Density: 0.989g/cm³
• Vapor Pressure: 0.0624mmHg at 25°C
• Refractive Index: 1.436
• CAS DataBase Reference: pentyl (2S)-2-hydroxypropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: pentyl (2S)-2-hydroxypropanoate(171056-23-8)
• EPA Substance Registry System: pentyl (2S)-2-hydroxypropanoate(171056-23-8)

Safety Data

• Hazardous Substances Data: 171056-23-8(Hazardous Substances Data)

Upstream product

• 547-64-8 methyl lactate 
• 71-41-0 pentan-1-ol 
• 3458-28-4 D-Mannose 
• 78-98-8 2-oxopropanal 
• 849585-22-4 LACTIC ACID 
• 814-80-2 calcium lactate 
• 312-85-6 sodium lactate 

Relevant articles and documents

Picolinic acid as a partner in the Mitsunobu reaction: Subsequent hydrolysis of picolinate esters under essentially neutral conditions with copper acetate in methanol

The use of picolinic acid and 6-methyl picolinic acid in the Mitsunobu reaction has been studied. These substrates are excellent partners in the Mitsunobu reaction, and offer the added advantage that the resulting esters can be cleaved under essentially neutral conditions using Cu(OAc)2 and methanol.

Method for preparing lactate

The invention relates to a method for preparing lactate. The method comprises the following steps: contacting pyruvic aldehyde and alcohol with a catalyst in a reactor, and reacting to obtain a lactate-containing product, wherein the molar ratio of the pyruvic aldehyde to the alcohol is 1:(20-225), the reaction temperature is 30-180 DEG C, the reaction time is 1-10 hours, the catalyst contains a mixture of a titanium-silicon molecular sieve and a tin-silicon molecular sieve, and the weight ratio of the pyruvic aldehyde to the mixture of the titanium-silicon molecular sieve and the tin-siliconmolecular sieve based on dry basis weight is 1:(0.1-6). The method provided by the invention has high pyruvic aldehyde conversion rate and high lactate yield.

ANTIVIRAL PRODRUGS OF TENOFOVIR

Compounds of Formula I: and pharmaceutically acceptable salts and co-crystals thereof are useful for the inhibition of HIV reverse transcriptase. The compounds may also be useful for the prophylaxis or treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antiviral agents, immunomodulators, antibiotics or vaccines.