171091-03-5Relevant articles and documents
Structural-activity relationship study on C-4 carbon atom of the CB 1 antagonist SR141716: Synthesis and pharmacological evaluation of 1,2,4-triazole-3-carboxamides
Jagerovic, Nadine,Hernandez-Folgado, Laura,Alkorta, Ibon,Goya, Pilar,Martin, Maria Isabel,Dannert, Maria Teresa,Alsasua, Angela,Frigola, Jordi,Cuberes, Maria Rosa,Dordal, Alberto,Holenz, Joerg
, p. 114 - 120 (2007/10/03)
A series of 1,2,4-triazole-3-carboxamides has been prepared from alkyl-1,2,4-triazole-3-carboxylates under mild conditions. The ability of these triazoles to displace [3H]-CP55940 from CB1 cannabinoid receptor was measured. However,