17122-21-3

Basic information

• Product Name: 1-nitro-3-nitrosobenzene
• Synonyms: 1-nitro-3-nitrosobenzene
• CAS NO: 17122-21-3
• Molecular Formula: C₆H₄N₂O₃
• Molecular Weight: 152.11
• Mol File: 17122-21-3.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 274.54°C (rough estimate)
• Flash Point: 120.3°C
• Appearance: /
• Density: 1.5327 (rough estimate)
• Vapor Pressure: 0.00858mmHg at 25°C
• Refractive Index: 1.4738 (estimate)
• CAS DataBase Reference: 1-nitro-3-nitrosobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-nitro-3-nitrosobenzene(17122-21-3)
• EPA Substance Registry System: 1-nitro-3-nitrosobenzene(17122-21-3)

Safety Data

• Hazardous Substances Data: 17122-21-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H4N2O3/c9-7-5-2-1-3-6(4-5)8(10)11/h1-4H

Upstream product

• 79-21-0 peracetic acid 
• 99-09-2 3-nitro-aniline 
• 267412-38-4 N-hydroxy-N-(3-nitrophenyl)acetamide 
• 7664-93-9 sulfuric acid 
• 64-17-5 ethanol 
• 6418-00-4 N-(3-nitrophenyl)hydroxylamine 
• 7705-08-0 iron(III) chloride 
• 1516-59-2 3-nitrophenyl azide 
• 99-65-0 meta-dinitrobenzene 

Downstream Products

• 106783-05-5 1-[3-(3-nitro-phenylazo)-phenyl]-ethanone 
• 106782-72-3 (E)-3-nitro-4'-acetoazobenzene 
• 77350-56-2 4-(3'-nitrophenylazo)-anisole 
• 4827-19-4 (3-nitro-phenyl)-phenyl-diazene 
• 318515-01-4 (E)-1,2-bis(3-nitrophenyl)diazene 
• 105971-14-0 (4-bromo-phenyl)-(3-nitro-phenyl)-diazene 
• 142640-33-3 C₁₆H₂₁N₅O₉S 
• 1516-59-2 3-nitrophenyl azide 
• 1230-85-9 3,3'-dinitro azoxybenzene 
• 4771-08-8 N-(3-nitrophenyl)benzamide 
• 135330-13-1 2-(3-nitrophenylamino)-3-hydroxynaphthalene-1,4-dione 

Relevant articles and documents

Continuous Flow Synthesis of Azoxybenzenes by Reductive Dimerization of Nitrosobenzenes with Gel-Bound Catalysts

In the search for a new synthetic pathway for azoxybenzenes with different substitution patterns, an approach using a microfluidic reactor with gel-bound proline organocatalysts under continuous flow is presented. Herein the formation of differently substituted azoxybezenes by reductive dimerization of nitrosobenzenes within minutes at mild conditions in good to almost quantitative yields is described. The conversion within the microfluidic reactor is analyzed and used for optimizing and validating different parameters. The effects of the different functionalities on conversion, yield, and reaction times are analyzed in detail by NMR. The applicability of this reductive dimerization is demonstrated for a wide range of differently substituted nitrosobenzenes. The effects of these different functionalities on the structure of the obtained azoxyarenes are analyzed in detail by NMR and single-crystal X-ray diffraction. Based on these results, the turnover number and the turnover frequency were determined.

Azo aryl urea derivative, and preparation method and application thereof

The invention relates to an azo aryl urea derivative, and a preparation and an application thereof, and concretely discloses a compound represented by formula (I), or an optical isomer, a cis-trans-isomer or a pharmaceutically acceptable salt thereof, and a preparation method thereof. Definitions of substituent groups in the general formula are described in the specification and claims. The invention further discloses a composition containing the above compound, and an application thereof. The compound has excellent anticancer activity on HepG2 liver cancer cells, MGC803 gastric cancer cells,HCT116 colon cancer and the like.

Azobenzene-benzoylphenylureas as photoswitchable chitin synthesis inhibitors

Benzoylphenylureas (BPUs) are used as synthetic insect growth regulators for inhibiting chitin synthesis. Merging insecticidal BPUs with photoswitchable azobenzene generated photoresponsive chitin synthesis inhibitors. A prepared azobenzene-benzoylphenylurea can be activated upon irradiation with UV light, and shows 6-fold and 2-fold activity difference to armyworm (Mythimna separata) and German cockroach (Blattella germanica) sulfonylurea receptors, respectively. This is the first example of a photoswitchable BPU insecticide. The generation of such a photoresponsive BPU insecticide allows for modulation of the insecticidal activity by light, and may facilitate the spatiotemporal control over the sulfonylurea receptor and the mechanistic study of this kind of insecticide.