17137-22-3

Upstream product

• 920-39-8 isopropylmagnesium bromide 
• 104-55-2 3-phenyl-propenal 
• 103-64-0 bromostyrene 
• 78-84-2 isobutyraldehyde 

Downstream Products

• 108814-27-3 (E)-4-methyl-1-phenyl-1-penten-3-ol acetate 
• 68426-07-3 (+/-)-1-phenyl-5-methylpentan-3-ol 
• 3160-32-5 (1E)-4-methyl-1-phenylpent-1-en-3-one 
• 1314802-08-8 [(1E)-3-azido-4-methyl-1-penten-1-yl]-benzene 
• 81238-63-3 3,3-dimethyl-6-phenyl-1,2-dioxa-4-cyclohexene 
• 81238-70-2 (E)-4-hydroxy-4-methyl-1-phenyl-2-penten-1-one 
• 72486-22-7 4-Methyl-1-phenylpenta-1,3-diene 

Relevant academic research and scientific papers

PALLADIUM(0) CATALYZED REACTIONS OF 1,4-EPIPEROXIDES

The Pd(PPh3)4 catalyzed reaction of 2,3-saturated and 2,3-unsaturated 1,4-epiperoxides proceeds by courses markedly different from those of the previously reported transition metal catalyses.The Pd(0)-promoted reaction of 2,3-saturated epiperoxides gives the corresponding 4-hydroxy ketones and 1,4-diols as the major products.From 2,3-dedihydroepiperoxides are formed the corresponding 4-hydroxy enones, syn-1,2;3,4-diepoxides, and 1,4-diols.The results are interpreted in terms of competing Pd(0)/Pd(II) exchange mechanisms.Exposure of prostaglandin (PG) H2 methyl esterto Pd(PPh3)4 produces a mixture of methyl esters of PGD2, PGE2, PGF2α, and (5Z,8E,10E,12S)-12-hydroxy-5,8,10-heptadecatrienoic acid.