17150-65-1Relevant academic research and scientific papers
Thermodynamically controlled, dynamic binding of diols to a 1,2-BN cyclohexane derivative
Harlow, Gregory P.,Zakharov, Lev N.,Wu, Gang,Liu, Shih-Yuan
, p. 6650 - 6653 (2013)
The reversible covalent binding of diols to an N-Bn 1,2-BN cyclohexane has been studied by 11B and 1H NMR spectroscopy and single-crystal X-ray diffraction analysis. The activation barrier for the reversible B-N Lewis acid-base interaction has been measured by variable-temperature NMR with bound (2R,3R)-(-)-2,3-butanediol (Tc = -40 C, ΔGa = 11.2 ± 0.2 kcal mol -1). Deuterium labeling experiments demonstrate that ligand exchange is reversible and rapid at room temperature, and competitive binding studies establish diol association as a thermodynamically controlled process.
