17153-02-5Relevant articles and documents
Asymmetric synthesis of all stereoisomers of a-methylthreonine using an organocatalytic steglich rearrangement reaction as a key step
Dietz, Friedrich R.,Groeger, Harald
, p. 4208 - 4218 (2011/04/12)
An efficient synthetic route to all four stereoisomers of a-methylthreonine has been established. Each type of stereoisomer has been isolated in diastereomerically pure form and with an enantiomeric excess of at least 86% ee. The key step in this multi-st
Novel catalytic synthetic route to protected α-methyl threonine and the first asymmetric acetyl migration in a steglich rearrangement reaction
Dietz, Friedrich R.,Gr?ger, Harald
, p. 663 - 666 (2008/12/20)
A short synthetic route to protected α-methyl threonine 5 as a representative example for (protected) α-methylated α-amino-β- hydroxy acids bearing a stereogenic quaternary carbon center in α-position was developed. This multistep synthesis is based on th