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2-Fluoro-3,4-dimethoxybenzylchloride, with the molecular formula C9H10ClFO2, is a benzyl chloride derivative characterized by the presence of a fluoro atom and two methoxy groups attached to the benzene ring. This chemical compound is recognized for its significant reactivity in various chemical reactions, which makes it a valuable intermediate in the synthesis of a diverse array of compounds. Its versatile nature and reactivity are particularly appreciated in the creation of functionalized benzene derivatives, contributing to its importance in the fields of organic synthesis.

1716-43-4

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1716-43-4 Usage

Uses

Used in Pharmaceutical Industry:
2-Fluoro-3,4-dimethoxybenzylchloride is utilized as a key building block in organic synthesis for the development of pharmaceutical compounds. Its unique structure and reactivity allow for the creation of novel drug candidates with potential therapeutic applications, making it an essential component in the advancement of new medications.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Fluoro-3,4-dimethoxybenzylchloride serves as an intermediate in the synthesis of various agrochemicals. Its role in the production of compounds with pesticidal properties underscores its importance in developing effective solutions for crop protection and management.
Used in Organic Synthesis:
2-Fluoro-3,4-dimethoxybenzylchloride is employed as a versatile intermediate in organic synthesis for the production of a wide range of functionalized benzene derivatives. Its ability to participate in numerous chemical reactions facilitates the creation of complex molecules with specific properties, which are crucial in various chemical and material applications.

Check Digit Verification of cas no

The CAS Registry Mumber 1716-43-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,7,1 and 6 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1716-43:
(6*1)+(5*7)+(4*1)+(3*6)+(2*4)+(1*3)=74
74 % 10 = 4
So 1716-43-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H10ClFO2/c1-12-7-4-3-6(5-10)8(11)9(7)13-2/h3-4H,5H2,1-2H3

1716-43-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(chloromethyl)-2-fluoro-3,4-dimethoxybenzene

1.2 Other means of identification

Product number -
Other names 1-chloromethyl-2-fluoro-3,4-dimethoxy-benzene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1716-43-4 SDS

1716-43-4Relevant academic research and scientific papers

Ring-truncated deguelin derivatives as potent Hypoxia Inducible Factor-1α (HIF-1α) inhibitors

Kim, Ho Shin,Hong, Mannkyu,Lee, Su-Chan,Lee, Ho-Young,Suh, Young-Ger,Oh, Dong-Chan,Seo, Ji Hae,Choi, Hoon,Kim, Jun Yong,Kim, Kyu-Won,Kim, Jeong Hun,Kim, Joohwan,Kim, Young-Myeong,Park, So-Jung,Park, Hyun-Ju,Lee, Jeewoo

, p. 157 - 164 (2015/10/29)

A series of fluorophenyl and pyridine analogues of 1 and 2 were synthesized as ring-truncated deguelin surrogates and evaluated for their HIF-1α inhibition. Their structure-activity relationship was systematically investigated based on the variation of th

Syntheses of Fluorinated 2-Benzylimidazolines

Adejare, Adeboye,Miller, Duane D.

, p. 171 - 193 (2007/10/02)

Perturbation of the electronic properties of the phenyl ring of 2-benzylimidazoline without appreciable steric modification can be achieved by fluorine substitution on the phenyl ring.The effects of such perturbation on biological activity can be evaluated.Syntheses of several fluorinated synthetic intermediates and 2-benzylimidazolines are described.Fluorine coupling of ortho benzylic protons and ortho methoxy protons were found to be 0-1.3 Hz.

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