17168-38-6

Basic information

• Product Name: 3-Furancarboxylic acid, 2,5-dimethyl-4-phenyl-, methyl ester
• CAS NO: 17168-38-6
• Molecular Formula: C14H14O3
• Molecular Weight: 230.263
• Mol File: 17168-38-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-Furancarboxylic acid, 2,5-dimethyl-4-phenyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Furancarboxylic acid, 2,5-dimethyl-4-phenyl-, methyl ester(17168-38-6)
• EPA Substance Registry System: 3-Furancarboxylic acid, 2,5-dimethyl-4-phenyl-, methyl ester(17168-38-6)

Safety Data

• Hazardous Substances Data: 17168-38-6(Hazardous Substances Data)

Upstream product

• 105-45-3 acetoacetic acid methyl ester 
• 705-60-2 1-phenyl-2-nitroprop-1-ene 
• 705-60-2 (2-nitroprop-1-enyl)benzene 
• 121725-72-2 2-acetyl-3-phenyl-pent-4-enoic acid methyl ester 
• 108164-13-2 6-hydroxy-5-methoxycarbonyl-3,6-dimethyl-4-phenyl-5,6-dihydro-4H-1,2-oxazine-2-oxide 
• 89446-99-1 4-Oxo-3-phenyl-2-[1-piperidin-1-yl-eth-(E)-ylidene]-pentanoic acid methyl ester 
• 23326-27-4 Methyl 2-butynoate 

Downstream Products

• 104794-86-7 4-<2-Methoxycarbonylamino-5(6)-benzimidazolylcarbonyl>-1-(2,5-dimethyl-4-phenyl-3-furoyl)-piperazine 
• 104794-83-4 2,5-Dimethyl-3-<4-(3-nitro-4-acetamidobenzoyl)-piperazinocarbonyl>-4-phenylfuran 
• 104794-84-5 2,5-Dimethyl-3-<4-(3-nitro-4-aminobenzoyl)-piperazinocarbonyl>-4-phenylfuran 
• 104794-85-6 [4-(3,4-Diamino-benzoyl)-piperazin-1-yl]-(2,5-dimethyl-4-phenyl-furan-3-yl)-methanone 
• 104794-40-3 (2,5-Dimethyl-4-phenyl-furan-3-yl)-(4-pyridin-2-yl-piperazin-1-yl)-methanone 
• 104794-38-9 (4-Benzyl-piperazin-1-yl)-(2,5-dimethyl-4-phenyl-furan-3-yl)-methanone 
• 104794-39-0 4-(2,5-Dimethyl-4-phenyl-furan-3-carbonyl)-piperazine-1-carbaldehyde 
• 104794-37-8 2,5-Dimethyl-3--4-phenylfuran 
• 104794-41-4 (2,5-Dimethyl-4-phenyl-furan-3-yl)-(4-methyl-piperazin-1-yl)-methanone 
• 104794-36-7 2,5-Dimethyl-3-(N-furfurylcarbamoyl)-4-phenylfuran 
• 104794-42-5 (2,5-Dimethyl-4-phenyl-furan-3-yl)-morpholin-4-yl-methanone 
• 104794-81-2 4-Phenyl-2,5-dimethyl-3-(piperazinocarbonyl)furan 
• 104794-43-6 (2,5-Dimethyl-4-phenyl-furan-3-yl)-piperidin-1-yl-methanone 
• 104794-35-6 2,5-Dimethyl-3-(N,N-di-n-propylcarbamoyl)-4-phenylfuran 

Relevant articles and documents

Iodoenolcyclization. III. A General Approach to Tetrasubstituted Furans from 2-Alkenyl-1,3-Dicarbonyl Compounds.

2,3,4,5-tetrasubstituted furans were easily obtained from of 2-alkenyl-1,3-dicarbonyl compounds by an efficient three steps synthesis.

One-Pot Synthesis of 3-Methoxycarbonyl-2,5-dimethyl-4-substituted-phenylfurans

Reinvestigation of the reaction of 2-nitro-1-substituted-phenylpropanes (1-5) with methyl acetoacetate in presence of piperidine has furnished an improved one-pot synthesis of 3-methoxycarbonyl-2,5-dimethyl-4-substituted-phenylfurans (11-13).The intermediates of this reaction in a few cases have been isolated.