23326-27-4

Basic information

• Product Name: METHYL 2-BUTYNOATE
• Synonyms: TETROLIC ACID METHYL ESTER;METHYL TETROLATE;METHYL 2-BUTYNOATE;2-BUTYNOIC ACID METHYL ESTER;Methyl-2-Butynaote97%;Methyl2-butynoate=Methyltetrolate;Methyl 2-butynoate,97%;Methyl 2-butynoate, 97% 5GR
• CAS NO: 23326-27-4
• Molecular Formula: C₅H₆O₂
• Molecular Weight: 98.1
• Product Categories: Acetylenes;Acetylenic Carboxylic Acids & Their Derivatives
• Mol File: 23326-27-4.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 76-77 °C (80 mmHg)
• Flash Point: 45 °C
• Appearance: Clear colorless to yellow/Liquid
• Density: 0.98
• Vapor Pressure: 6mmHg at 25°C
• Refractive Index: 1.436-1.438
• Storage Temp.: Flammables area
• CAS DataBase Reference: METHYL 2-BUTYNOATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2-BUTYNOATE(23326-27-4)
• EPA Substance Registry System: METHYL 2-BUTYNOATE(23326-27-4)

Safety Data

• Hazard Codes: Xn
• Statements: 10-36/37/38-20/21/22
• Safety Statements: 16-36/37/39-26
• RIDADR: 1993
• HazardClass: 3.2
• PackingGroup: III
• Hazardous Substances Data: 23326-27-4(Hazardous Substances Data)

Usage

Chemical Properties

clear colorless to yellowish liquid

Uses

Methyl 2-Butynoate, is an alkynoate used in preparation of various compounds such as preparation of phenanthrenes/benzoindolyl carboxylates.

Synthesis Reference(s)

Synthesis, p. 1100, 1982 DOI: 10.1055/s-1982-30090

InChI:InChI=1/C5H6O2/c1-3-4-5(6)7-2/h1-2H3

Upstream product

• 67-56-1 methanol 
• 590-93-2 2-Butynoic acid 
• 1743-62-0 [acetyl(methoxycarbonyl)methylene]triphenylphosphorane 
• 186581-53-3 diazomethane 
• 4344-87-0 1,2-dihydro-5-methyl-3H-pyrazol-3-one 
• 108-26-9 3-methyl-2-pyrazoline-5-one 
• 201230-82-2 carbon monoxide 
• 74-99-7 prop-1-yne 
• 79-22-1 methyl chloroformate 

Downstream Products

• 33547-92-1 2-cyclohexyl-5-methyl-isoxazol-3-one 
• 135462-61-2 methyl 2-methoxy-4-methyl-5-phenyl-furan-3-carboxylate 
• 50983-22-7 1-Carbomethoxy-2-methylcyclohexa-1,4-dien 
• 151101-22-3 4-benzyloxy-(E)-but-2-enoic acid methyl ester 
• 159693-09-1 3-(4-Fluoro-phenyl)-5-methyl-isoxazole-4-carboxylic acid methyl ester 
• 3461-50-5 methyl trans-3-methylcinnamate 
• 70134-71-3 3,4-dibromo-1,2,5-oxadiazole 2-oxide 
• 188686-98-8 3-Bromo-5-methyl-isoxazole-4-carboxylic acid methyl ester 
• 4525-27-3 β-acetoxy-crotonic acid methyl ester 
• 41264-06-6 methyl 4,6-dimethyl-2-oxo-2H-pyran-5-carboxylate 
• 207225-49-8 2-butynoic acid (-)-menthol ester 
• 15346-85-7 Dimethyl 2,4-dihydroxy-6-methylbenzene-1,3-dicarboxylate 
• 126838-56-0 methyl 3,6-dimethoxy-2-methylbenzoate 
• 27349-35-5 5-methoxy-3-methyl-1-phenyl-1H-pyrazole 

Relevant articles and documents

Oxidative Methoxycarbonylation of Allene in the Presence of a Copper-Palladium Catalyst

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The detection of PHIP effects allows new insights into the mechanism of olefin isomerisation during catalytic hydrogenation

PHIP (parahydrogen-induced polarisation) effects in the 1H NMR spectra of the products of Rh-complex-catalysed alkyne hydrogenation brings to light the fact that the cis-trans isomerisation of the formed olefin occurs through the formation of a σ-bonded intermediate stabilised by the reversible addition of a hydrogen molecule at the metal centre. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.

Copper-Catalyzed Domino Synthesis of Benzo[4,5]imidazo[1,2-a]pyrimidin-4(10H)-ones using Cyanamide as a Building Block

An efficient and practical copper-catalyzed domino synthesis of benzo[4,5]imidazo[1,2-a]pyrimidin-4(10H)-ones has been developed. The protocol uses N-(2-halophenyl)-3-alkylpropiolamides and cyanamide as the starting materials, inexpensive copper(I) iodide and pipecolinic acid as the catalyst and ligand, and the corresponding products were obtained in moderate to good yields.

Synthesis and spectroscopic characterization of 1-13C- and 4-13C-plastoquinone-9

This paper presents the synthesis of 1-13C- and 4-13C-plastoquinone-9 and their characterization with NMR spectroscopy and mass spectrometry. The synthetic scheme has been further adapted to introduce 13C-labeled plastoquinones on all individual and on each combination of positions in the quinone ring. Also a two-step scheme is disclosed to prepare unlabeled plastoquinone-9. Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002.