1717-85-7Relevant academic research and scientific papers
Stereoselective Reduction of α-Fluoro-β-keto Esters by NADH and NADPH-Dependent Ketoreductases
Green, Thomas K.,Damarancha, Anil,Vanagel, Matthew,Showalter, Brandon,Kolberg, Sandra,Thompson, Alexander
supporting information, p. 4080 - 4084 (2019/06/21)
Racemic α-fluoro-β-keto esters were stereoselectively transformed to α-fluoro-β-hydroxy esters through dynamic reductive kinetic resolution (DYRKR) using commercially available NAD(P)H-dependent ketoreductases. Aromatic, alkenyl, and alkyl substrates were
