17173-27-2

Basic information

• Product Name: METHYL 2-(2-ACETYL-4,5-DIMETHOXYPHENYL)ACETATE
• Synonyms: METHYL 2-(2-ACETYL-4,5-DIMETHOXYPHENYL)ACETATE
• CAS NO: 17173-27-2
• Molecular Formula: C₁₃H₁₆O₅
• Molecular Weight: 252.26
• Mol File: 17173-27-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 376.1°Cat760mmHg
• Flash Point: 198.4°C
• Appearance: /
• Density: 1.137g/cm³
• Vapor Pressure: 7.44E-06mmHg at 25°C
• Refractive Index: 1.503
• CAS DataBase Reference: METHYL 2-(2-ACETYL-4,5-DIMETHOXYPHENYL)ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2-(2-ACETYL-4,5-DIMETHOXYPHENYL)ACETATE(17173-27-2)
• EPA Substance Registry System: METHYL 2-(2-ACETYL-4,5-DIMETHOXYPHENYL)ACETATE(17173-27-2)

Safety Data

• Hazardous Substances Data: 17173-27-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H16O5/c1-8(14)10-7-12(17-3)11(16-2)5-9(10)6-13(15)18-4/h5,7H,6H2,1-4H3

Upstream product

• 105-45-3 acetoacetic acid methyl ester 
• 866252-52-0 4,5-dimethoxy-2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 93-40-3 (3,4-Dimethoxyphenyl)acetic acid 
• 4697-57-8 methyl 2-(2-bromo-4,5-dimethoxyphenyl)acetate 
• 15964-79-1 methyl (3,4-dimethoxyphenyl)acetate 
• 108-24-7 acetic anhydride 
• 50516-11-5 7-acetoxyoctanoic acid 

Downstream Products

• 3809-00-5 4,5-dimethoxyhomophthalic acid 
• 144709-31-9 3<2-(methoxycarbonylmethyl)-4,5-dimethoxyphenyl>-1,7,8-trimethoxyisoquinoline 
• 144709-24-0 N-methyl-3<2-(methoxycarbonylmethyl)-4,5-dimethoxyphenyl>-6,7-dimethoxy-1(2H)-isoquinolone 
• 144709-22-8 3-<2-(methoxycarbonyl-methyl)-4,5-dimethoxyphenyl>-6,7-dimethoxy-1(2H)-isoquinolone 
• 144709-30-8 N-methyl-3-<2-(methoxycarbonylmethyl)-4,5-dimethoxyphenyl>-7,8-dimethoxy-1(2H)-isoquinolone 
• 144709-28-4 3-<2-(methoxycarbonylmethyl)-4,5 dimethoxyphenyl>-7,8-dimethoxy-1(2H)-isoquinolone 
• 144709-25-1 3<2-(methoxycarbonylmethyl)-4,5-dimethoxyphenyl>1,6,7-trimethoxy-isoquinoline 
• 144709-33-1 [2-(7,8-Dimethoxy-1-oxo-1,2-dihydro-isoquinolin-3-yl)-4,5-dimethoxy-phenyl]-acetic acid 
• 144709-21-7 [2-(6,7-Dimethoxy-1-oxo-1,2-dihydro-isoquinolin-3-yl)-4,5-dimethoxy-phenyl]-acetic acid 
• 144709-32-0 N-methyl-3-<2-(hydroxyethyl)-4,5-dimethoxyphenyl>-7,8-dimethoxy-1(2H)-isoquinolone 
• 144709-23-9 3-<2-(hydroxyethyl)-4,5-dimethoxyphenyl>6,7-dimethoxy-1(2H)-isoquinolone 
• 144709-29-5 3-<2-(hydroxyethyl)-4,5-dimethoxyphenyl>-7,8-dimethoxy-1(2H)-isoquinolone 
• 136540-25-5 3-<2-(2-hydroxyethyl)-4,5-dimethoxyphenyl>-6,7-dimethoxy-2-methylisoquinolin-1-<2H>-one 
• 221189-56-6 2-hydroxy-6,7-dimethoxy-3-(2-nitrophenyl)-1,4-naphthoquinone 

Relevant articles and documents

Synthesis of Air- and Moisture-Stable, Storable Chiral Oxorhenium Complexes and Their Application as Catalysts for the Enantioselective Imine Reduction

Air-/moisture-stable, crystalline, and storable chiral salicyloxazoline based oxorhenium(V) complexes have been synthesized and their catalytic application for the asymmetric reduction of ketimines using hydrosilane as hydride source is disclosed. A broad substrate scope, high yields, and excellent enantioselectivities (up to 99 %) are attained. Furthermore, the syntheses of enantiopure α-amino esters, γ- and δ-lactams, and isoindolinones have also been carried out using this methodology. Finally, the method has been applied to synthetic targets of pharmaceutical relevance, such as R-(+)-salsolidine and R-(+)-crispine A.

Palladium mediated total synthesis of o-acetylphenylacetic acids: A general route to indolo[2,3-b]naphthalene-6,11-diones

Here we describe a new, efficient general synthesis of o-acetylphenylacetic acids by Heck palladium-catalyzed arylation of n-butyl vinyl ether with o-bromophenylacetic acids, and its application to the synthesis of indolo[2,3-b]naphthalene-6,11-diones.