221189-56-6

Upstream product

• 17173-25-0 2-hydroxy-6,7-dimethoxynaphthalene-1,4-dione 
• 1493-27-2 ortho-nitrofluorobenzene 
• 278801-02-8 methyl 2-[2-(2-nitrophenyl)acetyl]-4,5-dimethoxyphenylacetate 
• 477338-27-5 6,7-Dimethoxy-3-[1-(2-nitro-phenyl)-meth-(Z)-ylidene]-isochroman-1,4-dione 
• 19193-05-6 3,4-dihydro-4-keto-6,7-dimethoxyisocoumarin 
• 17667-32-2 methyl 6-bromo-3,4-dimethoxybenzoate 
• 58657-20-8 4',5'-Dimethoxy-2'-carboxyacetophenon 
• 477338-24-2 methyl 2-acetyl-4,5-dimethoxybenzoate 
• 477338-25-3 2-(2-Bromo-acetyl)-4,5-dimethoxy-benzoic acid 
• 477338-23-1 methyl methyl 2-(1-butoxyvinyl)-4,5-dimethoxybenzoate 
• 4697-57-8 methyl 2-(2-bromo-4,5-dimethoxyphenyl)acetate 
• 17173-27-2 methyl 2-(2-acetyl-4,5-dimethoxyphenyl)acetate 
• 1207515-13-6 C₁₈H₁₅NO₆ 

Relevant academic research and scientific papers

Gold-facilitated '6-exo-dig' intramolecular cyclization of 2-[(2-nitrophenyl)ethynyl]phenylacetic acids: General access to 5H-benzo[b]carbazole-6,11-diones

The preliminary results of a regiospecific synthesis of (Z)-1 -(2-nitrobenzylidene)isochroman-3-ones by gold(I)-catalyzed cycloisomerization of phenylethynylacetic acids under mild conditions is described. These novel lactones proved to be suitable starti

Palladium-catalyzed synthesis of o-acetylbenzoic acids: A new, efficient general route to 2-hydroxy-3-phenyl-1,4-naphthoquinones and indolo[2,3-b]naphthalene-6,11-diones

We describe here a new, efficient general synthesis of o-acetylbenzoic acids by Heck palladium-catalyzed arylation of n-butyl vinyl ether with o-bromobenzoic acid esters and the use of these compounds as starting materials for the synthesis of 3-benzylideneisochroman-1,4-diones, which readily rearrange to 2-hydroxy-3-phenyl-1,4-naphthoquinones. The application of this strategy to the synthesis of indolo[2,3-b]naphthalene-6,11-diones is also described.

From phenylacetylphenylacetic acids to indoles: A simple new divergent synthesis of 6,11-dihydro-5H-benzo[a]carbazol-5,6-diones and 6,11-dihydro-5H-benzo[b]carbazol-6,11-diones

The synthesis 6,11-dihydro-5H-benzo[a]carbazole-5,6-diones and 6,11-dihydro-5H-benzo[b]carbazole-6,11-diones from common starting materials, 1-(2′-nitrophenylacetyl)phenylacetic acids is described.

Palladium mediated total synthesis of o-acetylphenylacetic acids: A general route to indolo[2,3-b]naphthalene-6,11-diones

Here we describe a new, efficient general synthesis of o-acetylphenylacetic acids by Heck palladium-catalyzed arylation of n-butyl vinyl ether with o-bromophenylacetic acids, and its application to the synthesis of indolo[2,3-b]naphthalene-6,11-diones.

A simple synthesis of benzocarbazolequinones via o-nitroarylation of 2- hydroxy-1,4-naphthoquinones

The reaction of 2-hydroxy-1,4-naphthoquinones (1a-c) with o- fluoronitrobenzenes (2a,b) in the presence of K2CO3 in DMSO at 100 °C gave 2-hydroxy-3-(2-nitroaryl)-1,4-naphthoquinones (3a-e) in moderate to fair yields, which in turn we