17179-91-8

Usage

Type of compound

dicarboxylic acid (contains two carboxylic acid functional groups)

Physical form

white crystalline solid

Solubility

soluble in water and organic solvents

Uses

intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds; production of food additives, flavorings, and fragrances; potential applications in materials science and as a building block for the synthesis of novel polymers and materials.

InChI:InChI=1/C7H12O4/c1-4(3-6(8)9)5(2)7(10)11/h4-5H,3H2,1-2H3,(H,8,9)(H,10,11)

Upstream product

• 876504-08-4 2-hydroxy-2,3-dimethyl-glutaric acid 
• 10034-85-2 hydrogen iodide 
• 64-17-5 ethanol 
• 34611-32-0 2-cyano-3,4-dimethyl-glutaric acid diethyl ester 
• 151-50-8 potassium cyanide 
• 903639-00-9 2-cyano-2,3-dimethyl-glutaric acid 
• 17225-74-0 N-(2-Hydroxy-ethyl)-N-methyl-propionamide 
• 623-70-1 ethyl (E)-crotonate 
• 609-08-5 Diethyl methylmalonate 
• 623-43-8 crotonic acid methyl ester 
• 107932-60-5 (S)-N-methyl-N-propionylvalinol 
• 74036-66-1 (S)-(-)-prolinol propionamide 
• 138500-84-2 2,3-dimethyl-glutaric acid-anhydride 
• 7732-18-5 water 

Downstream Products

• 110-15-6 succinic acid 

Relevant academic research and scientific papers

Urea compounds as inhibitors for vla-4

A compound of formula (I) where D is a VLA-4 specificity determinant which does not impart significant IIB/IIIa activity; R41 is a group of the formula (V): U - (CH2)d - V - T wherein U is selected from oxygen, sulphur, a direct bond or —CH2O—, V is selected from nitrogen, oxygen, sulphur, S(O), S(O)2 or a direct bond, d is zero or a number from 1 to 4, and T is selected from a range of variables defined in the application; and other variables are defined in the application, or a pharmaceutically acceptable salt or in vivo hydrolysable derivative thereof. The compounds are useful in the treatment of disease mediated by the interaction between VCAM-1 and/or fibronectin and the integrin receptor α4β1. Pharmaceutical compositions and methods of use or treatment are also described and claimed.

Enzymes in organic synthesis, 26: Synthesis of enantiomerically enriched 2,3- and 3,4-dimethylpentan-5-olides by lipase-catalyzed regio- and enantioselective alcoholysis of cis- and trans-2,3-dimethylpentanedioic anhydrides

The enzyme-catalyzed regio- and enantioselective alcoholysis of racemic cis- and trans-2,3-dimethylpentanedioic anhydride in the presence of Novozym 435 from Candida antarctica afforded two of the eight possible monoesters with an enantiomeric excess higher than 90%. Regioselective reductions of these monoesters with lithium borohydride or borane/dimethyl sulfide furnished four enantiomerically highly enriched dimethylpentan-5-olides, which are versatile chiral intermediates. VCH Verlagsgesellschaft mbH, 1996.

A DIASTEREO- AND ENANTIOSELECTIVE MICHAEL ADDITION OF CHIRAL AMIDE ENOLATES TO α,β-UNSATURATED ESTERS; A STEREOSELECTIVE SYNTHESIS OF (+)-DEHYDROIRIDODIOL AND (-)-ISODEHYDROIRIDODIOL

(+)-Dehydroiridodiol and (-)-isodehydroiridodiol were synthesized stereoselecticely using the diastereo- and enantioselective Michael addition of chiral amide enolates to α,β-unsaturated esters.