171820-17-0

Basic information

• Product Name: 2,5-bis-(4-methoxyphenyl)-pyridine
• Synonyms: 2,5-bis-(4-methoxyphenyl)-pyridine
• CAS NO: 171820-17-0
• Molecular Formula: C₁₉H₁₇NO₂
• Molecular Weight: 291.34378
• Mol File: 171820-17-0.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,5-bis-(4-methoxyphenyl)-pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-bis-(4-methoxyphenyl)-pyridine(171820-17-0)
• EPA Substance Registry System: 2,5-bis-(4-methoxyphenyl)-pyridine(171820-17-0)

Safety Data

• Hazardous Substances Data: 171820-17-0(Hazardous Substances Data)

Usage

General Description

2,5-bis-(4-methoxyphenyl)-pyridine is a chemical compound that consists of a pyridine ring with two 4-methoxyphenyl substituents. It is commonly used in organic synthesis and pharmaceutical research due to its potential biological activities. 2,5-bis-(4-methoxyphenyl)-pyridine has been studied for its antioxidant, anti-inflammatory, and anti-cancer properties, making it a valuable target for drug development. Additionally, its unique structure and reactivity make it a useful building block for the synthesis of more complex organic molecules. Overall, 2,5-bis-(4-methoxyphenyl)-pyridine has a wide range of applications in the field of chemistry and biomedicine, and its versatility makes it an important chemical compound in scientific research and industrial processes.

Upstream product

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Downstream Products

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Relevant articles and documents

Coumarin-pyridine push-pull fluorophores: Synthesis and photophysical studies

A series of coumarin-pyridine-based push-pull fluorophores were prepared starting from 1,2,4-triazines by using direct C-H functionalization (SNH-reaction)–Diels-Alder–retro Diels-Alder domino reaction sequence. This efficient synthetic strategy allowed to obtain a series of 19 coumarin-pyridine fluorophores. Their photophysical properties were studied. While pyridine-substituted derivatives of 4-alkylcoumarins may be considered as alternative to coumarin dyes characterized by emission maxima mainly in a visible region with wavelengths of 402–415 nm, absorption in the UV range at 210–307 nm, and good photoluminescence quantum yields of 6–19%, all the derivatives of 4-phenylcoumarin did not exhibit any noticeable fluorescence. More detailed photophysical studies were carried out for two the most representative derivatives of 4-alkyl-coumarin-pyridines to demonstrate their positive solvatochromism, and the collected data were analyzed by using Lippert-Mataga equation, as well as Kosower and Dimroth/Reichardt scales. The obtained results demonstrate that the combining two chromophore systems, such as 2,5-diarylpyridine and coumarin ones, is promising in terms of improving the photophysical properties of the new coumarin-pyridine hybrid compounds.

Efficient Suzuki-Miyaura mono-arylation of symmetrical diiodo(hetero)arenes

A reliable protocol for converting 1,4-diiodo-2,3,5,6-tetrafluorobenzene into 1-(hetero)aryl-4-iodo-2,3,5,6-tetrafluorobenzene derivatives has been lacking in the literature. We have identified optimal conditions to achieve this conversion in good yields and have minimized formation of the bis-coupling product. The newly identified protocol involving the use of a syringe pump has been extended to other symmetrical diiodo(hetero)arenes.

Synthesis of 2,5- and 3,5-diphenylpyridine derivatives for DNA recognition and cytotoxicity

A series of 2,5- and 3,5-diphenylpyridine derivatives was synthetised in high yields. A versatile chemical strategy allows the design of diphenylpyridines differently substituted with cationic or neutral side chains. The interaction of the molecules with