171860-41-6

Basic information

• Product Name: (2S,4S)-3-Benzyloxycarbonyl-4-methyl-2-phenyl-1,3-oxazolidin-5-one
• Synonyms: (2S,4S)-3-BENZYLOXYCARBONYL-4-METHYL-2-PHENYL-1,3-OXAZOLIDIN-5-ONE;(2S, 4S) Z-5-OXAZOLIDINONE(2-PH, 4-ME);Benzyl (2S,4S)-4-methyl-5-oxo-2-phenyl-1,3-oxazolidine-3-carboxylate
• CAS NO: 171860-41-6
• Molecular Formula: C₁₈H₁₇NO₄
• Molecular Weight: 311.33
• Mol File: 171860-41-6.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 509.982 °C at 760 mmHg
• Flash Point: 262.228 °C
• Appearance: /
• Density: 1.246
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.585
• CAS DataBase Reference: (2S,4S)-3-Benzyloxycarbonyl-4-methyl-2-phenyl-1,3-oxazolidin-5-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4S)-3-Benzyloxycarbonyl-4-methyl-2-phenyl-1,3-oxazolidin-5-one(171860-41-6)
• EPA Substance Registry System: (2S,4S)-3-Benzyloxycarbonyl-4-methyl-2-phenyl-1,3-oxazolidin-5-one(171860-41-6)

Safety Data

• Hazardous Substances Data: 171860-41-6(Hazardous Substances Data)

Usage

General Description

(2S,4S)-3-Benzyloxycarbonyl-4-methyl-2-phenyl-1,3-oxazolidin-5-one is a chemical compound with the molecular formula C16H17NO3. It is a chiral oxazolidinone derivative that is commonly used as a reagent in organic synthesis. (2S,4S)-3-Benzyloxycarbonyl-4-methyl-2-phenyl-1,3-oxazolidin-5-one is a white crystalline solid that is typically used as a protected intermediate for the synthesis of peptides and other biologically active molecules. Its specific stereochemistry and functional groups make it a versatile building block for the preparation of various pharmaceuticals, agrochemicals, and other organic compounds. (2S,4S)-3-Benzyloxycarbonyl-4-methyl-2-phenyl-1,3-oxazolidin-5-one is stable under normal conditions and is commercially available for use in research and development laboratories.

InChI:InChI=1/C18H17NO4/c1-13-17(20)23-16(15-10-6-3-7-11-15)19(13)18(21)22-12-14-8-4-2-5-9-14/h2-11,13,16H,12H2,1H3/t13-,16-/m0/s1

Upstream product

• 56-41-7 L-alanin 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 113806-26-1 Sodium; (S)-2-{[1-phenyl-meth-(E)-ylidene]-amino}-propionate 
• 501-53-1 benzyl chloroformate 
• 1142-20-7 N-Cbz-Ala 
• 100-52-7 benzaldehyde 
• 35364-99-9 α-chlorobenzyl methyl ether 

Downstream Products

• 177696-13-8 (2S,4S)-4-Benzylsulfanylmethyl-4-methyl-5-oxo-2-phenyl-oxazolidine-3-carboxylic acid benzyl ester 
• 330795-80-7 (R,S)-4-(4-bromobenzyl)-4-methyl-5-oxo-2-phenyl-oxazolidine-3-carboxylic acid benzyl ester 
• 951172-59-1 (2S,4S)-3-benzyloxycarbonyl-4-methyl-2-phenyl-4-(prop-2-enyl)oxazolidin-5-one 
• 951172-65-9 (3R)-3-benzyloxycarbonylamino-3-methyl-1-(3-phthalimidopropyl)pyrrolidin-2-one 
• 951172-68-2 (3R)-3-benzyloxycarbonylamino-3-methyl-1-(3-phthalimidopropyl)pyrrolidine-2-thione 
• 951172-70-6 (3R)-3-benzyloxycarbonylamino-3-methyl-1-(3-aminopropyl)pyrrolidine-2-thione 
• 951172-71-7 methyl 3-benzylamino-2-(phthalimidomethyl)propanoate 
• 951172-74-0 (3R)-3-benzyloxycarbonylamino-3-methyl-1-((2RS)-2-methoxycarbonyl-3-phthalimidopropyl)pyrrolidine-2-thione 
• 951172-76-2 (3R)-3-benzyloxycarbonylamino-3-methyl-1-((2RS)-3-amino-2-methoxycarbonylpropyl)pyrrolidine-2-thione 
• 951172-78-4 (3S,7S)-7-benzyloxycarbonylamino-3-methoxycarbonyl-3,7-dimethyl-1,5-diazabicyclo[4.3.0]non-5-ene 
• 951172-79-5 (3S,7S)-7-benzyloxycarbonylamino-3-carboxy-3,7-dimethyl-1,5-diazabicyclo[4.3.0]non-5-ene 
• 951172-60-4 (2S,4S)-3-benzyloxycarbonyl-4-methyl-4-(2-oxoethyl)-2-phenyloxazolidin-5-one 
• 951172-62-6 (3R)-3-benzyloxycarbonylamino-3-methyl-1-(p-methoxyphenyl)pyrrolidin-2-one 

Relevant articles and documents

ASPARAGINE DERIVATIVES AND METHODS OF USE THEREOF

The present invention relates to compounds of formulas (A) and (I), pharmaceutically acceptable salts thereof, and solvates of any of them, pharmaceutical compositions comprising them, methods of preparation thereof, intermediate compounds useful for the preparation thereof, and methods of treatment or prophylaxis of diseases, in particular cancer, such as colorectal cancer, using these. (A) (I)

RAS INHIBITORS

The disclosure features macrocyclic compounds, and pharmaceutical compositions and protein complexes thereof, capable of inhibiting Ras proteins, and their uses in the treatment of cancers.

CYCLIZED SULFAMOYLARYLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B

Inhibitors of HBV replication of Formula (I-A), including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein Ra to Rd, and R1 to R8 have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.