171973-38-9

Basic information

• Product Name: 1-(2-O-tosyl-3,5-di-O-benzoyl-β-D-xylofuranosyl)thymine
• Synonyms: 1-(2-O-tosyl-3,5-di-O-benzoyl-β-D-xylofuranosyl)thymine
• CAS NO: 171973-38-9
• Molecular Weight: 620.637
• Mol File: 171973-38-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2-O-tosyl-3,5-di-O-benzoyl-β-D-xylofuranosyl)thymine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-O-tosyl-3,5-di-O-benzoyl-β-D-xylofuranosyl)thymine(171973-38-9)
• EPA Substance Registry System: 1-(2-O-tosyl-3,5-di-O-benzoyl-β-D-xylofuranosyl)thymine(171973-38-9)

Safety Data

• Hazardous Substances Data: 171973-38-9(Hazardous Substances Data)

Upstream product

• 7288-28-0 2,4-bis(trimethylsiloxy)-5-methylpyrimidine 
• 117257-96-2 1-(2-O-acetyl-3,5-di-O-benzoyl-β-D-xylofuranosyl)thymine 
• 85026-60-4 (3R,4S,5R)-4-(benzoyloxy)-5-((benzoyloxy)methyl)tetrahydrofuran-2,3-diyl diacetate 
• 98-59-9 p-toluenesulfonyl chloride 
• 99152-42-8 1-(3',5'-di-O-benzoyl-β-D-xylo-furanosyl)thymine 

Downstream Products

• 3056-17-5 stavudin 
• 122567-97-9 5′-benzoyl-2′,3′-didehydro-3′-deoxythymidine 

Relevant articles and documents

SYNTHESIS OF 2',3'-DIDEHYDRO-3'-DEOXYTHYMIDINE AND ITS ACTIVITY AGAINST HIV

2,3-Didehydro-3'-deoxythymidine has been obtained with an overall yield of 10percent by the condensation of 1,2-di-O-acetyl-3,5-di-O-benzoyl-D-xylofuranose with bis(dimethylsilyl)thymine and a series of subsequent transformations.The anti-HIV activity of the compound obtained was studied on the model of MT-4 lymphoid cells primarily infected with HIV-1.It was found that the substance effectively inhibits the reproduction of HIV-1 in a cell culture.