172034-33-2Relevant academic research and scientific papers
New Approach to the Coupling if γ-Amino β-Hydroxy Acids and ν,γ-Dihydroxy Acids with α-Amino Acid Esters
Palomo, Claudio,Miranda, Jose I.,Linden, Anthony
, p. 9196 - 9201 (2007/10/03)
α,α-Dichloro β-lactones, readily obtained by a highly diastereoselective cycloaddition of dichloroketene to N-Boc-α-amino aldehydes and α-(silyloxy) aldehydes, coupled efficiently with α-amino acid esters leading, after dehalogenation with H2 over 10percent Pd on charcoal, to peptide mimics under mild reaction conditions.
Diastereoselective Cycloaddition of Dichloroketene with α-Oxyaldehydes and α-Amino Aldehydes
Palomo, Claudio,Miranda, Jose Ignacio,Cuevas, Carmen,Odriozola, Jose Manuel
, p. 1735 - 1736 (2007/10/02)
A new route to natural products containing 1,2-diol and 1,2-amino alcohol subunits based on the cycloaddition of dichloroketene to α-oxyaldehydes and α-amino aldehydes is demonstrated.
