172089-88-2Relevant academic research and scientific papers
Homologues of anti-HIV active isodideoxynucleosides
Bolon, Pascal,Jahnke, Tamera S.,Nair, Vasu
, p. 10443 - 10452 (1995)
The synthesis of a homologous series of compounds related to the anti-HIV active class of compounds known as (S,S)-isodideoxynucleosides has been completed by a convergent route using a modified carbohydrate intermediate. This precursor, synthesized from D-glucose, was coupled with a variety of natural purine and pyrimidine bases to regiospecifically afford the desired new class of compounds.
