Tetrahedron p. 10443 - 10452 (1995)
Update date:2022-08-03
Topics:
Bolon, Pascal
Jahnke, Tamera S.
Nair, Vasu
The synthesis of a homologous series of compounds related to the anti-HIV active class of compounds known as (S,S)-isodideoxynucleosides has been completed by a convergent route using a modified carbohydrate intermediate. This precursor, synthesized from D-glucose, was coupled with a variety of natural purine and pyrimidine bases to regiospecifically afford the desired new class of compounds.
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