1722-90-3

Usage

General Description

2-Propenamide, N-methyl-3,3-diphenyl- is an organic compound commonly known as N-methyl-N-phenylacrylamide. It is a clear, colorless liquid with a slightly chemical odor, often used as a monomer in the production of polymers. This chemical is commonly used in the production of polyacrylamides, which are a class of water-soluble polymers with applications in various industries including wastewater treatment, papermaking, and oil recovery. It is also used as a crosslinking agent in the production of resins and adhesives. Additionally, it is used as a stabilizer for some plastics and a co-monomer in the production of specialty polymers. It is important to handle this chemical with care as it has toxic and irritant properties when inhaled or in contact with skin.

Upstream product

• 1210-39-5 3,3-diphenyl-2-propenal 
• 38359-28-3 N-methyl-9H-fluoren-9-amine 
• 123-39-7 N-Methylformamide 
• 530-48-3 1,1-Diphenylethylene 
• 4456-79-5 3,3-diphenylacryloyl chloride 
• 593-51-1 methylamine hydrochloride 
• 74-89-5 methylamine 

Downstream Products

• 2584-37-4 1-methyl-4-phenyl-1H-quinolin-2-one 

Relevant academic research and scientific papers

Cu-Catalyzed carbamoylation: Versus amination of quinoline N -oxide with formamides

An efficient, direct carbamoylation and amination of quinoline N-oxides with formamides to access 2-carbamoyl and 2-amino quinolines has been developed through copper-catalyzed C-C and C-N bond formations via cross-dehydrogenative coupling reactions. The reaction proceeds smoothly over a broad range of substrates with excellent functional group tolerance under mild conditions. Mechanistic studies suggest that the reaction is initiated by formamide radical or decarbonylative aminyl radical formation in the presence of TBHP, according to the different substituent on the N atom of formamide.

Aminofluorene-Mediated Biomimetic Domino Amination-Oxygenation of Aldehydes to Amides

A conceptually novel biomimetic strategy based on a domino amination-oxygenation reaction was developed for direct amidation of aldehydes under metal-free conditions employing molecular oxygen as the oxidant. 9-Aminofluorene derivatives acted as pyridoxamine-5′-phosphate equivalents for efficient, chemoselective, and operationally simple amine-transfer oxygenation reaction. Unprecedented RNH transfer involving secondary amine to produce secondary amides was achieved. In the presence of 18O2, 18O-amide was formed with excellent (95%) isotopic purity.

Palladium-catalyzed intramolecular amidation of C(sp2)-H bonds: Synthesis of 4-aryl-2-quinolinones

Figure presented A catalytic synthetic approach for the synthesis of 2-quinolinone compounds through a Pd-catalyzed C(sp2)-H functionalization/intramolecular amidation sequence is described. The cyclization process efficiently proceeds in the p