38359-28-3

Basic information

• Product Name: 9H-Fluoren-9-amine, N-methyl-
• Synonyms: methylaminofluorene;9-(N-Methylamino)fluorene;Fluoren-9-yl-methyl-amin;fluorenylmethylamine;9H-Fluoren-9-amine,N-methyl;FLUOREN-9-YL-METHYLAMINE
• CAS NO: 38359-28-3
• Molecular Formula: C14H13N
• Molecular Weight: 195.26000
• Mol File: 38359-28-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 9H-Fluoren-9-amine, N-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 9H-Fluoren-9-amine, N-methyl-(38359-28-3)
• EPA Substance Registry System: 9H-Fluoren-9-amine, N-methyl-(38359-28-3)

Safety Data

• Hazardous Substances Data: 38359-28-3(Hazardous Substances Data)

Upstream product

• 6638-65-9 N-(9H-fluoren-9-yl)formamide 
• 70402-38-9 9-bromo-9-methyl-fluorene 
• 7664-41-7 ammonia 
• 108-88-3 toluene 
• 4440-33-9 fluorenone imine 
• 486-25-9 9-fluorenone 
• 525-03-1 9-aminofluorene 
• 1493-54-5 N-(9-fluorenyl)trifluoroacetamide 
• 74-88-4 methyl iodide 
• 60734-27-2 N-(9H-fluoren-9-ylidene)methanamine 
• 81532-35-6 benzaldehyde 9-fluorenyl imine 

Downstream Products

• 186907-17-5 9-(N-p-toluenesulfonyl-N-methylamino)fluorene 
• 3400-22-4 4-methoxy-N-methylbenzamide 
• 6873-44-5 p-chloro-N-methylbenzamide 
• 1722-90-3 N-methyl-3,3-diphenylacrylamide 
• 186907-16-4 9-(N-benzoyloxy-N-methylamino)fluorene 
• 186907-20-0 9-(N-4-nitrobenzenesulfonyl-N-methylamino)fluorene 
• 186907-19-7 9-(N-4-bromobenzenesulfonyl-N-methylamino)fluorene 
• 186907-18-6 9-(N-4-methoxybenzenesulfonyl-N-methylamino)fluorene 

Relevant articles and documents

Aminofluorene-Mediated Biomimetic Domino Amination-Oxygenation of Aldehydes to Amides

A conceptually novel biomimetic strategy based on a domino amination-oxygenation reaction was developed for direct amidation of aldehydes under metal-free conditions employing molecular oxygen as the oxidant. 9-Aminofluorene derivatives acted as pyridoxamine-5′-phosphate equivalents for efficient, chemoselective, and operationally simple amine-transfer oxygenation reaction. Unprecedented RNH transfer involving secondary amine to produce secondary amides was achieved. In the presence of 18O2, 18O-amide was formed with excellent (95%) isotopic purity.

Mechanisms of solvent- and base-promoted imine-forming elimination reactions

Solvolysis of 9-(N-chloro-N-methylamino)fluorene (1-Cl) in 25 vol % acetonitrile in water gives the imine fluorenylidenemethylamine (3) as the sole product. The kinetic deuterium isotope effect was measured with the deuterated analogue (9-2H)-9