172269-40-8

Upstream product

• 172269-36-2 (S)-4-benzyl-3-{(2S,3R,4R)-3-hydroxy-5-[(4methoxybenzyl)oxy]-2,4-dimethylpentanoyl}oxazolidin-2-one 
• 212051-35-9 (R)-methyl 3-((4-methoxybenzyl)oxy)-2-methylpropanoate 
• 160238-46-0 (2R)-3-(4-methoxybenzyloxy)-2-methyl-1-propanal 
• 160238-45-9 (2S)-3-(4-methoxybenzyloxy)-2-methyl-1-propanol 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 

Downstream Products

• 1040727-24-9 (1S,3R,4R,5S)-3-((R)-1-{(4R,5R,6S)-6-[(S)-1-(benzyloxy)propano-2-yl]-2,2,5-trimethyl-1,3-dioxan-4-yl}ethyl)-1,4-dimethyl-2,8-dioxabicyclo[3.2.1]octane 
• 208984-65-0 C₆₄H₁₁₈O₈Si₄ 
• 208984-61-6 C₆₃H₁₂₀O₈SSi₄ 
• 208984-62-7 C₆₃H₁₂₂O₈SSi₄ 
• 208984-47-8 (2R,4R,5R)-4-[(Z)-(1S,2S,3R,7R,8S,9R)-2,8-Bis-(tert-butyl-dimethyl-silanyloxy)-10-(4-methoxy-benzyloxy)-1,3,5,7,9-pentamethyl-dec-5-enyl]-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxane 
• 208984-48-9 (Z)-(2R,3S,4R,8R,9S,10S)-3,9-Bis-(tert-butyl-dimethyl-silanyloxy)-10-[(2R,4R,5R)-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxan-4-yl]-2,4,6,8-tetramethyl-undec-5-en-1-ol 
• 208984-49-0 (2R,4R,5R)-4-[(Z)-(1S,2S,3R,7R,8S,9S)-2,8-Bis-(tert-butyl-dimethyl-silanyloxy)-10-iodo-1,3,5,7,9-pentamethyl-dec-5-enyl]-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxane 
• 172269-24-8 (R)-1-Benzyloxy-3-{2-[(1S,2S,3S)-2-(tert-butyl-dimethyl-silanyloxy)-4,4-dimethoxy-1,3-dimethyl-butyl]-[1,3]dithian-2-yl}-propan-2-ol 

Relevant academic research and scientific papers

Synthesis of the C4-C17 fragment of saliniketals a and b

A highly stereoselective synthesis of the C4-C17 fragment of saliniketals A and B was completed. The key steps in this synthesis included a syn-aldol reaction mediated by a boron enolate and a double diastereodifferentiating aldol reaction mediated by a titanium enolate. Moreover, a substrate-controlled Grignard reaction, an intramolecular Wacker-type cyclization and a Seyferth-Gilbert homologation provided the C4-C17 fragment of saliniketals A and B in 16 steps and with a 7 % overall yield. Copyright