17230-47-6

Upstream product

• 488-76-6 (-)-viburnitol 
• 98-88-4 benzoyl chloride 
• 17278-12-5 D-1,3,4/2,5-cyclohexanepentol 
• 73803-07-3 L-1,3,4,5,6-penta-O-benzoyl-chiro-inositol 
• 74-88-4 methyl iodide 
• 73763-43-6 L-1,3,4,5,6-penta-O-benzoyl-2-O-formyl-chiro-inositol 
• 73803-06-2 L-1,3,4,5,6-penta-O-benzoyl-2-O-methyl-chiro-inositol 

Downstream Products

• 17278-12-5 D-1,3,4/2,5-cyclohexanepentol 
• 310872-40-3 Phosphoric acid benzyl ester (R)-2-methoxy-3-octadecyloxy-propyl ester (1R,2R,3S,6R)-2,3,6-tris-benzyloxy-cyclohexyl ester 
• 310872-38-9 C₃₀H₃₄O₄ 
• 310872-39-0 (1R,2S,3S,6R)-2,3,6-Tris-benzyloxy-cyclohexanol 
• 310872-37-8 (1R,2R,3R,4S)-2-Allyloxy-3,4-bis-benzyloxy-cyclohexanol 
• 310872-36-7 (1R,2R,3S,4S)-3,4-Bis-benzyloxy-cyclohexane-1,2-diol 

Relevant academic research and scientific papers

Synthesis and Akt inhibitory properties of a 1D-3,4-dideoxyphosphatidylinositol ether lipid

1D-3,4-Dideoxyphosphatidylinositol ether lipid 2, a PI analog, was synthesized through a sequence of protection/deprotection protocols and two Barton deoxygenation reactions, starting from L-(-)-quebrachitol. DDPIEL is 18-fold more potent than its monodeoxy counterpart DPIEL in the inhibition of PI3-K. (C) 2000 Published by Elsevier Science Ltd.

Synthesis and evaluation of glucocerebrosidase inhibitory activity of anhydro deoxyinositols from (+)-epi- and (-)-vibo-quercitols

Twelve 1,2- and 2,3-anhydro-1,2,3,4,5-cyclohexanepentols were synthesized from (+)-epi- and (-)-vibo-quercitols, readily available by bioconversion of myo-inositol, and assayed for inhibitory activity against glucocerebrosidase (mouse liver). Among them 1L-1,2-anhydro-1,2,4/3,5- cyclohexanepentol, the 3-deoxy derivative of the irreversible inhibitor conduritol B epoxide (CBE), has been demonstrated to be a highly potent and specific inhibitor, almost comparable to the parent compound.