73803-07-3Relevant academic research and scientific papers
Synthesis and Akt inhibitory properties of a 1D-3,4-dideoxyphosphatidylinositol ether lipid
Hu,Meuillet,Qiao,Berggren,Powis,Kozikowski
, p. 7415 - 7418 (2007/10/03)
1D-3,4-Dideoxyphosphatidylinositol ether lipid 2, a PI analog, was synthesized through a sequence of protection/deprotection protocols and two Barton deoxygenation reactions, starting from L-(-)-quebrachitol. DDPIEL is 18-fold more potent than its monodeoxy counterpart DPIEL in the inhibition of PI3-K. (C) 2000 Published by Elsevier Science Ltd.
Anchimerically Assisted Demethylation of Methyl Ethers in Inositol Derivatives with an AlCl3-NaI System
Akiyama, Takahiko,Takechi, Naoto,Shima, Hiroaki,Ozaki, Shoichiro
, p. 1881 - 1884 (2007/10/02)
Investigated are AlCl3 and NaI catalyzed chemoselective demethylation reactions of methyl ethers of partly protected inositol derivatives, reactions which are greatly promoted by vicinal OH group and proceed in preference to the cleavage of the cis cyclohexylidene moiety.
SYNTHESIS OF 1D- AND 1L-4-O-BENZYL-myo-INOSITOL, 1D-4-O-α-L-FUCOPYRANOSYL-myo-INOSITOL (IDENTICAL TO A NATURAL GLYCOSIDE), AND 1L-4-O-α-L-FUCOPYRANOSYL-myo-INOSITOL
Garegg, Per J.,Lindberg, Bengt,Kvarnstroem, Ingemar,Svensson, Stefan C. T.
, p. 209 - 216 (2007/10/02)
The α-L-fucopyranosyl-myo-inositol isolated from human urine has been proved to be the 1D-4-O-myo-inositol derivative by unambiguous syntheses of this substance and of the diastereomeric 1L-4-O-myo-inositol derivative.The chiral penta-O-benzoyl-myo-inosit
