172405-47-9Relevant articles and documents
Dde-protected PNA monomers, orthogonal to Fmoc, for the synthesis of PNA-peptide conjugates
Bialy, Laurent,Díaz-Mochón, Juan José,Specker, Edgar,Keinicke, Lise,Bradley, Mark
, p. 8295 - 8305 (2005)
Peptide nucleic acids have become, arguably, one of the most interesting of DNA mimics. Herein the efficient solution phase synthesis of four novel 1-(4,4-dimethyl-2,6-dioxacyclohexylidene)ethyl/4-methoxytrityl (Dde/Mmt) protected PNA monomers is reported
Synthesis of polyamide nucleic acids (PNAs) using a novel Fmoc/Mmt protecting-group combination
Breipohl,Knolle,Langner,O'Malley,Uhlmann
, p. 665 - 670 (2007/10/03)
The preparation of 9-Fluorenylmethoxycarbonyl(Fmoc) protected building blocks for the synthesis of polyamide nucleic acids (PNAs) is described. Use of 4-Methoxyphenyldiphenylmethyl (Mmt)-protecting groups for the exocyclic amino function of the nucleobase