17245-30-6

Usage

Uses

Used in Pharmaceutical Industry:
3',4',5',3,5,6,7-Heptamethoxyflavone is used as a potential therapeutic agent for its antioxidant, anti-inflammatory, and anti-cancer properties. It is being studied for its potential in treating various health conditions, although further research is required to fully understand its therapeutic potential.
Used in Nutraceutical Industry:
In the nutraceutical industry, 3',4',5',3,5,6,7-Heptamethoxyflavone is used as a dietary supplement for its health-promoting properties, including its antioxidant and anti-inflammatory effects, which may contribute to overall well-being and disease prevention.
Used in Cosmetic Industry:
3',4',5',3,5,6,7-Heptamethoxyflavone is used as an ingredient in cosmetic products for its potential skin health benefits, such as its antioxidant properties that may help protect the skin from environmental damage and promote a youthful appearance.

Upstream product

• 124909-81-5 6-hydroxy-3,5,7-trimethoxy-2-(3,4,5-trimethoxy-phenyl)-chromen-4-one 
• 77-78-1 dimethyl sulfate 
• 30250-35-2 5,7-dihydroxy-3,3',4',5',6-pentamethoxyflavone 
• 14639-73-7 1-(3,6-dihydroxy-2,4-dimethoxy-phenyl)-2-methoxy-ethanone 
• 1719-88-6 3,4,5-trimethoxybenzoic anhydride 

Downstream Products

• 17245-31-7 5'-hydroxy-3,6,7,3',4',5'-hexamethoxyflavone 
• 124909-91-7 Toluene-4-sulfonic acid 3,6,7-trimethoxy-4-oxo-2-(3,4,5-trimethoxy-phenyl)-4H-chromen-5-yl ester 
• 124909-98-4 Toluene-4-sulfonic acid 3-hydroxy-6,7-dimethoxy-4-oxo-2-(3,4,5-trimethoxy-phenyl)-4H-chromen-5-yl ester 
• 124910-07-2 Acetic acid 3-acetoxy-6,7-dimethoxy-4-oxo-2-(3,4,5-trimethoxy-phenyl)-4H-chromen-5-yl ester 
• 72357-39-2 3,5-Dihydroxy-6,7-dimethoxy-2-(3,4,5-trimethoxy-phenyl)-chromen-4-one 

Relevant academic research and scientific papers

Use of flavone and flavanone derivatives in preparation of sedative and hypnotic drugs

Disclosed is a use of flavones derivatives and flavanone derivatives in preparation of sedative and hypnotic drugs.

Antivascular and anti-parasite activities of natural and hemisynthetic flavonoids from New Caledonian Gardenia species (Rubiaceae)

A series of 16 flavonoids were isolated and prepared from bud exudate of Gardenia urvillei and Gardenia oudiepe, endemic to New Caledonia. Most of them are rare polymethoxylated flavones. Some of these compounds showed noticeable activity against Leishmania (Leishmania) amazonensis, Plasmodium falciparum and Trypanosoma brucei gambiense, in addition to tubulin polymerization inhibition at low micromolar concentration. We also provide a full set of NMR data as some of the flavones were incompletely described.

STUDIES OF THE SELECTIVE O-ALKYLATION AND DEALKYLATION OF FLAVONOIDS. XII. A NEW, CONVENIENT METHOD FOR SYNTHESIZING 3,5-DIHYDROXY-6,7-DIMETHOXYFLAVONES FROM 3,5,6,7-TETRAMETHOXYFLAVONES

The 5-methoxy group on 3,5,6,7-tetramethoxyflavones and the 3-methoxy group on 3,6,7-trimethoxy-5-tosyloxy-flavones were selectively cleaved with anhydrous aluminum bromide in acetonitrile under controlled conditions without the cleavage of benzyloxy groups on the B ring.By the application of these reactions, seven 3,5-dihydroxy-6,7-dimethoxyflavones were easily synthesized from the corresponding 3,5,6,7-tetramethoxyflavones which were synthesized from 3,6-dihydroxy-2,4ω-trimethoxycetophenone by means of the Allan-Robinson reaction followed by methylation.Keywords: Allan-Robinson reaction ; selective demethylation; 3,5,6,7-tetramethoxyflavone; 5-hydroxy-3,6,7-trimethoxyflavone; 6-hydroxy-3,5,7-trimethoxyflavone; 5-tosyloxyflavone; 5,6-dihydroxy-3,7-dimethoxyflavone; 3,5-dihydroxy-6,7-dimethoxyflavone, 3,5-diacetoxy-6,7-dimethoxyflavone