3',4',5',3,5,6,7-Heptamethoxyflavone

Base Information

• Chemical Name: 3',4',5',3,5,6,7-Heptamethoxyflavone
• CAS No.: 17245-30-6
• Molecular Formula: C22H24 O9
• Molecular Weight: 432.427
• Hs Code.: 2932999099
• Mol file: 17245-30-6.mol

Synonyms:Flavone,3,3',4',5,5',6,7-heptamethoxy- (7CI,8CI); 3,3',4',5,5',6,7-Heptamethoxyflavone;3,5,6,7,3',4',5'-Heptamethoxyflavone; 3',4',5',3,5,6,7-Heptamethoxyflavone; NSC684433

Chemical Property of 3',4',5',3,5,6,7-Heptamethoxyflavone

Chemical Property:

• PSA: 94.82000
• LogP: 3.52020
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

3',4',5',3,5,6,7-Heptamethoxyflavone 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3',4',5',3,5,6,7-Heptamethoxyflavone

There total 6 articles about 3',4',5',3,5,6,7-Heptamethoxyflavone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5,7-dihydroxy-3,3',4',5',6-pentamethoxyflavone (30250-35-2) + dimethyl sulfate (77-78-1) → 5'-hydroxy-3,6,7,3',4',5'-hexamethoxyflavone (17245-31-7) + 3,5,6,7,3',4',5'-hepta methoxyl-flavone (17245-30-6)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetone; at 20 ℃; for 1h; Overall yield = 86 %; Inert atmosphere;

DOI:10.1016/j.ejmech.2015.01.012

Reference yield:

3,4,5-trimethoxybenzoic anhydride (1719-88-6) → 3,5,6,7,3',4',5'-hepta methoxyl-flavone (17245-30-6)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium-<3,4,5-trimethoxy benzoate> / 180 °C / unter vermindertem Druck und Erwaermen des Reaktionsprodukts mit aethanol. Kalilauge

2: acetone; potassium carbonate

With sodium 3,4,5-trimethoxybenzoate; potassium carbonate; acetone;

Reference yield:

1-(3,6-dihydroxy-2,4-dimethoxy-phenyl)-2-methoxy-ethanone (14639-73-7) → 3,5,6,7,3',4',5'-hepta methoxyl-flavone (17245-30-6)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium-<3,4,5-trimethoxy benzoate> / 180 °C / unter vermindertem Druck und Erwaermen des Reaktionsprodukts mit aethanol. Kalilauge

2: acetone; potassium carbonate

With sodium 3,4,5-trimethoxybenzoate; potassium carbonate; acetone;

upstream raw materials:

6-hydroxy-3,5,7-trimethoxy-2-(3,4,5-trimethoxy-phenyl)-chromen-4-one

dimethyl sulfate

3,4,5-trimethoxybenzoic anhydride

1-(3,6-dihydroxy-2,4-dimethoxy-phenyl)-2-methoxy-ethanone

Downstream raw materials:

5'-hydroxy-3,6,7,3',4',5'-hexamethoxyflavone

3,5-Dihydroxy-6,7-dimethoxy-2-(3,4,5-trimethoxy-phenyl)-chromen-4-one

Acetic acid 3-acetoxy-6,7-dimethoxy-4-oxo-2-(3,4,5-trimethoxy-phenyl)-4H-chromen-5-yl ester

Toluene-4-sulfonic acid 3-hydroxy-6,7-dimethoxy-4-oxo-2-(3,4,5-trimethoxy-phenyl)-4H-chromen-5-yl ester