17249-79-5

Basic information

• Product Name: 2,3-Dichlorothiophene
• Synonyms: 2,3-DICHLOROTHIOPHENE;2,3-Dchlorothiophene;2,3-DICHLOROPYRIDINE;Thiophene, 2,3-dichloro-;2,3-Dichlorothiophene,97%
• CAS NO: 17249-79-5
• Molecular Formula: C₄H₂Cl₂S
• Molecular Weight: 153.03
• Product Categories: Thiophens;Halogenated Heterocycles;Heterocyclic Building Blocks;Thiophenes;ThiophenesBuilding Blocks;Heterocycle-oher series
• Mol File: 17249-79-5.mol
• Article Data: 3

Chemical Properties

• Melting Point: -26 °C
• Boiling Point: 173-174 °C760 mm Hg(lit.)
• Flash Point: 159 °F
• Appearance: Clear colorless to pale yellow/Liquid
• Density: 1.456 g/mL at 25 °C(lit.)
• Vapor Pressure: 1.93mmHg at 25°C
• Refractive Index: n20/D 1.5680(lit.)
• Storage Temp.: 2-8°C
• BRN: 1760
• CAS DataBase Reference: 2,3-Dichlorothiophene(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Dichlorothiophene(17249-79-5)
• EPA Substance Registry System: 2,3-Dichlorothiophene(17249-79-5)

Safety Data

• Hazard Codes: T
• Statements: 25-43
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 2810 6.1/PG 3
• WGK Germany: 3
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 17249-79-5(Hazardous Substances Data)

Usage

Chemical Properties

Colorless liquid

Uses

Reactant for:Synthesis of enediyne-chlorophyll derivatives as antitumor cytotoxic conjugatesSelective electrochemical mono- and polysilylation

InChI:InChI=1/C4H2Cl2S/c5-3-1-2-7-4(3)6/h1-2H

Upstream product

• 17249-80-8 3-chlorothiophene 
• 17249-75-1 2,4-dichlorothiophene 
• 64048-11-9 2,3,4,5-tetrachloro-tetrahydro-thiophene 
• 31166-29-7 4,5-dichlorothiophene-2-carboxylic acid 

Downstream Products

• 31166-29-7 4,5-dichlorothiophene-2-carboxylic acid 
• 1969-60-4 Acenaphtho<1,2-b>thiophene 
• 57681-59-1 1-(4,5-Dichlor-2-thienyl)-ethanon 
• 90048-69-4 (4,5-Dichloro-thiophen-2-yl)-oxo-acetic acid ethyl ester 
• 126714-85-0 2,3-dichlorothiophene-5-sulfonyl chloride 
• 49600-07-9 2,3-dichloro-5-nitro-thiophene 
• 59337-89-2 3-chlorothiophene-2-carboxylic acid 
• 40477-46-1 2,3-dibromo-4,5-dichloro-thiophene 
• 83663-36-9 5-bromo-2,3-dichlorothiophene 
• 122065-05-8 2,3-dichloro-5-chloromethyl-thiophene 

Relevant articles and documents

Polychlorination of Thiophene. A Reinvestigation

Some old controversies in the literature with regard to the structures of trichlorothiophenes have been elucidated.In the course of these studies, we found that the best method for the preparation of 2,3,5-trichlorothiophene is the direct chlorination of thiophene in the presence of catalytic amounts of ferric chloride.If 2,5-dichlorothiophene is available 2,3,5-trichlorothiophene can also be obtained in good yields through chlorination with thionyl chloride and sulfuryl chloride, using aluminum trichloride as catalyst.

Sulfonation of aromatic compounds in the presence of solvents

A process for the sulfonation of aromatic compounds wherein an aromatic substance consisting of one or more aromatic compounds susceptible to the action of sulfur trioxide is formed into a reactant by admixture with one or more organic liquids, substantially inert to sulfur trioxide under the conditions of the process, which reactant is brought to boiling at a temperature not greater than 100° C under a pressure of from 0.1 mm Hg to atmospheric pressure, gaseous sulfur trioxide is introduced thereinto thereby causing it to continue to boil, the component or components of the reactant thus volatilized is or are reconverted to liquid in a heat-exchanger and recycled to the reaction chamber, and the pressure in the reaction chamber and the rate at which the gaseous sulfur trioxide is introduced into the reactant are controlled so as to ensure that there is always present in the reaction chamber an amount of volatilizable matter exceeding that amount volatilizable by the heat of reaction of the aromatic substance present in the reaction chamber with the gaseous sulfur trioxide in contact with said aromatic substance and that the temperature of the reaction mixture is a temperature of 100° C or below.