1725-32-2 Usage
General Description
10-Chloro-10, 11-dihydro-dibenz(b,f)thiepin, also known as Clomipramine, is a tricyclic antidepressant medication that is used to treat obsessive-compulsive disorder (OCD) in adults and children over the age of 10. It works by restoring the balance of certain natural substances in the brain (such as serotonin) to improve mood, feelings of well-being, and decrease anxiety and unwanted thoughts. It is thought to act by increasing the activity of serotonin, a substance in the brain that helps maintain mental balance. This medication is available in tablet form and is typically taken once or twice daily. As with many medications, Clomipramine may cause side effects including nausea, drowsiness, dry mouth, and constipation. It is important to consult with a healthcare professional before starting or discontinuing the use of this medication.
Check Digit Verification of cas no
The CAS Registry Mumber 1725-32-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,7,2 and 5 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1725-32:
(6*1)+(5*7)+(4*2)+(3*5)+(2*3)+(1*2)=72
72 % 10 = 2
So 1725-32-2 is a valid CAS Registry Number.
InChI:InChI=1/C14H11ClS/c15-12-9-10-5-1-3-7-13(10)16-14-8-4-2-6-11(12)14/h1-8,12H,9H2
1725-32-2Relevant articles and documents
Synthesis and biological activity of 11-[4-(cinnamyl)-1-piperazinyl]-6,11-dihydrodibenz[b,e]oxepin derivatives, potential agents for the treatment of cerebrovascular disorders
Kurokawa,Sato,Masuda,Yoshida,Ochi,Zushi,Fujiwara,Naruto,Uno,Matsumoto
, p. 2564 - 2573 (2007/10/02)
A series of 11-[4-(cinnamyl)-1-piperazinyl]-6,11-dihydrodibenz[b,e]oxepins and related compounds were synthesized and evaluated for their protective activities against complete ischemia, normobaric hypoxia, lipidperoxidation and convulsion. Structure-activity relationship studies of this series led to the finding of (E)-1-(3-fluoro-6,11-dihydrodibenz[b,e]oxepin-11-yl)-4-(3-phenyl-2-prop enyl)piperazine dimaleate (50), AJ-3941 with the most appropriate property for combined pharmacological activities. Compound 50 also shows an inhibitory effect against cerebral edema as well when orally given to rats.
