1725-32-2 Usage
Uses
Used in Pharmaceutical Industry:
10-Chloro-10, 11-dihydro-dibenz(b,f)thiepin is used as a tricyclic antidepressant for the treatment of obsessive-compulsive disorder (OCD) in adults and children over the age of 10. It is utilized for its ability to restore the balance of serotonin in the brain, thereby improving mood, feelings of well-being, and reducing anxiety and unwanted thoughts.
Used in Mental Health Treatment:
Clomipramine is employed as a therapeutic agent for individuals suffering from OCD, helping to alleviate the symptoms of the disorder by modulating the brain's serotonin levels. This medication is particularly beneficial for those who have not responded well to other treatments or who require a more targeted approach to managing their condition.
Check Digit Verification of cas no
The CAS Registry Mumber 1725-32-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,7,2 and 5 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1725-32:
(6*1)+(5*7)+(4*2)+(3*5)+(2*3)+(1*2)=72
72 % 10 = 2
So 1725-32-2 is a valid CAS Registry Number.
InChI:InChI=1/C14H11ClS/c15-12-9-10-5-1-3-7-13(10)16-14-8-4-2-6-11(12)14/h1-8,12H,9H2
1725-32-2Relevant academic research and scientific papers
Synthesis and biological activity of 11-[4-(cinnamyl)-1-piperazinyl]-6,11-dihydrodibenz[b,e]oxepin derivatives, potential agents for the treatment of cerebrovascular disorders
Kurokawa,Sato,Masuda,Yoshida,Ochi,Zushi,Fujiwara,Naruto,Uno,Matsumoto
, p. 2564 - 2573 (2007/10/02)
A series of 11-[4-(cinnamyl)-1-piperazinyl]-6,11-dihydrodibenz[b,e]oxepins and related compounds were synthesized and evaluated for their protective activities against complete ischemia, normobaric hypoxia, lipidperoxidation and convulsion. Structure-activity relationship studies of this series led to the finding of (E)-1-(3-fluoro-6,11-dihydrodibenz[b,e]oxepin-11-yl)-4-(3-phenyl-2-prop enyl)piperazine dimaleate (50), AJ-3941 with the most appropriate property for combined pharmacological activities. Compound 50 also shows an inhibitory effect against cerebral edema as well when orally given to rats.
