172535-87-4

Basic information

• Product Name: N-(4-bromo-5-methoxy-2-nitrophenyl)-2,2,2-trifluoroacetamide
• Synonyms: N-(4-bromo-5-methoxy-2-nitrophenyl)-2,2,2-trifluoroacetamide
• CAS NO: 172535-87-4
• Molecular Weight: 343.057
• Mol File: 172535-87-4.mol

Chemical Properties

• CAS DataBase Reference: N-(4-bromo-5-methoxy-2-nitrophenyl)-2,2,2-trifluoroacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-bromo-5-methoxy-2-nitrophenyl)-2,2,2-trifluoroacetamide(172535-87-4)
• EPA Substance Registry System: N-(4-bromo-5-methoxy-2-nitrophenyl)-2,2,2-trifluoroacetamide(172535-87-4)

Safety Data

• Hazardous Substances Data: 172535-87-4(Hazardous Substances Data)

Upstream product

• 77337-82-7 1-bromo-2-methoxy-4-nitrobenzene 
• 16133-49-6 5-methoxy-2-nitroaniline 
• 173312-36-2 4-bromo-5-methoxy-2-nitrobenzeneamine 
• 407-25-0 trifluoroacetic anhydride 
• 19056-40-7 4-bromo-3-methoxyaniline 

Downstream Products

• 172535-88-5 N-(4-Bromo-5-methoxy-2-nitro-phenyl)-oxalamic acid ethyl ester 
• 173312-36-2 4-bromo-5-methoxy-2-nitrobenzeneamine 

Relevant articles and documents

Acetoxylation of 6,7-dialkoxy-substituted 1,4-dihydroquinoxaline-2,3-diones (QXs) using fuming nitric acid in acetic acid: A facile synthesis of 5-acyloxy-6,7-dialkoxy QXs

Treatment of 6,7-dialkoxy-1,4-dihydroquinoxaline-2,3-diones 3 with fuming nitric acid in acetic acid at 25°C resulted in an acetoxylation reaction, giving 5-acetoxy-6,7-dialkoxy-1,4-dihydroquinoxaline-2,3-diones 4 in moderate yields. A mechanism involving ipso attack of nitronium ion as the first step is proposed.

HETEROCYCLIC AND HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE

The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. Formula (I). In particular, the present description relates to substituted bicyclic heterocyclic and heteroaryl compounds compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.