Acetoxylation of 6,7-dialkoxy-substituted 1,4-dihydroquinoxaline-2,3-diones (QXs) using fuming nitric acid in acetic acid: A facile synthesis of 5-acyloxy-6,7-dialkoxy QXs

DOI: 10.1016/0040-4039(95)01562-V

Source and publish data:

Tetrahedron Letters p. 7583 - 7586 (1995)

Update date:2022-07-29

Topics:

Authors:

Zhou, Zhang-Lin

Weber, Eckard

Keana, John F. W.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(95)01562-V

Treatment of 6,7-dialkoxy-1,4-dihydroquinoxaline-2,3-diones 3 with fuming nitric acid in acetic acid at 25°C resulted in an acetoxylation reaction, giving 5-acetoxy-6,7-dialkoxy-1,4-dihydroquinoxaline-2,3-diones 4 in moderate yields. A mechanism involving ipso attack of nitronium ion as the first step is proposed.

Full text of DOI:10.1016/0040-4039(95)01562-V

Products guided by the article

Product name:N-(4-bromo-5-methoxy-2-nitrophenyl)-2,2,2-trifluoroacetamide

Cas No:172535-87-4

R&D Labs maybe for 172535-87-4

Fuxin Jintelai Fluorin Chemical Co., Ltd.

Contact:+86-0418-8229599

Address:, 7th Huagong Road, Fluorine industry development zone (Yimatu Town,Fumeng County),Fuxin City, Liaoning Province, China
Suqian Ruixing Chemical Co., Ltd.

Contact:+86-527-80805666（总机）;84836008(销售)

Address:3 Jingsilu, Zone north, Hubin Xincheng Development Park, Suqian, China
ENERGYCO LTD.

Contact:+86-25-83719363

Address:106-7 Chunnan Rd, Chunxi Town, Gaochun, Nanjing, China
Changsha Botaniex Inc.

Contact:(86) 731 88718666

Address:Room 1222, Unit 4, Building B, Shangcheng, No.47, Kaiyuan East Road.
H&Y International Group Ltd

Contact:+86-571-86491666

Address:SHI XIANG ROAD

Relevant to this article

Ruthenium-alkylidene catalysed cross-metathesis of fatty acid derivatives with acrylonitrile and methyl acrylate: A key step toward long-chain bifunctional and amino acid compounds

Doi:10.1039/c1gc15569e
(2011)
Short and Linear Intermolecular Tetrel Bonds to Tin. Cocrystal Engineering with Triphenyltin Chloride

Doi:10.1021/acs.cgd.9b01681
(2020)
3-[2-(N-phenylacetamide)]-1,5-benzodiazepines: Orally active, binding selective CCK-A agonists

Doi:10.1021/jm960205b
(1996)
Studies of the cyclocondensation of o-aminophenyl-substituted ketoximes and amidoximes with carbonyl compounds giving quinazoline derivatives

Doi:10.1002/ardp.19953280502
(1995)
Simple synthesis of enantiomerically pure, protected cis-bicyclo[4.4.0]decane-1-carboxaldehyde derivatives from cyclohexanones by the 3-arenesulfonyloxazolidine route

Doi:10.1055/s-1996-4170
(1996)
Synthesis of a double-phospholipid

Doi:10.1016/0040-4039(95)02163-9
(1996)

Article Doi