172732-78-4Relevant articles and documents
Synthesis and chemical transformation of 2-iodomethyl-1-(phenylmethyl)-1,5, 6,7-tetrahydroindol-4-ones
Mphahlelea, Malose J.,El-Gogary, Tarek M.
experimental part, p. 227 - 231 (2009/08/07)
2-Allyl-3-benzylamino-2-cyclohexenones undergo iodine-methanol-promoted iodocyclisation under reflux to afford products characterised by combination of NMR (1H and 13C), IR and mass spectroscopic techniques as the conjugated iodolium betaine derivatives o
PHOSPHOLIPASE INHIBITORS, INCLUDING MULTI-VALENT PHOSPHOLIPASE INHIBITORS, AND USE THEREOF, INCLUDING AS LUMEN-LOCALIZED PHOSPHOLIPASE INHIBITORS
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Page/Page column 187-197; 212-213; 216; 219-220; 263-264; 265; 271, (2010/11/27)
The present invention provides methods and compositions for the treatment of phospholipase-related conditions. In particular, the invention provides a method of treating insulin-related, weight-related conditions and/or cholesterol-related conditions in an animal subject. The method generally involves the administration of a non-absorbed and/or effluxed phospholipase A2 inhibitor that is localized in a gastrointestinal lumen.
Multivalent indole compounds and use thereof as phospholipase-A2 inhibitors
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Page/Page column 91-97; 108-109; 112-115, (2010/11/27)
Indole and indole-related compounds, compositions and methods are disclosed. The compounds of the invention are useful as phospholipase inhibitors. The compounds and compositions of the invention are useful for treatment of phospholipase-related conditions, such as insulin-related, weight-related and/or cholesterol-related conditions in an animal subject.