936567-95-2

Upstream product

• 105-36-2 ethyl bromoacetate 
• 172732-78-4 4-hydroxy-2-methyl-1-(phenylmethyl)-1H-indole 

Downstream Products

• 936567-96-3 (1-benzyl-2-methyl-1H-indol-4-yloxy)-acetic acid 
• 936625-80-8 (1-benzyl-4-ethoxycarbonylmethoxy-2-methyl-1H-indol-3-yl)-oxoacetic acid 

Relevant academic research and scientific papers

PHOSPHOLIPASE INHIBITORS, INCLUDING MULTI-VALENT PHOSPHOLIPASE INHIBITORS, AND USE THEREOF, INCLUDING AS LUMEN-LOCALIZED PHOSPHOLIPASE INHIBITORS

The present invention provides methods and compositions for the treatment of phospholipase-related conditions. In particular, the invention provides a method of treating insulin-related, weight-related conditions and/or cholesterol-related conditions in an animal subject. The method generally involves the administration of a non-absorbed and/or effluxed phospholipase A2 inhibitor that is localized in a gastrointestinal lumen.

INDOLE COMPOUNDS HAVING C4-ACIDIC SUBSTITUENTS AND USE THEREOF AS PHOSPHOLIPASE-A2 INHIBITORS

Indole and indole-related compounds, compositions and methods are disclosed. The compounds of the invention are useful as phospholipase inhibitors. The compounds and compositions of the invention are useful for treatment of phospholipase-related conditions, such as insulin-related, weight-related and/or cholesterol-related conditions in an animal subject.

Multivalent indole compounds and use thereof as phospholipase-A2 inhibitors

Indole and indole-related compounds, compositions and methods are disclosed. The compounds of the invention are useful as phospholipase inhibitors. The compounds and compositions of the invention are useful for treatment of phospholipase-related conditions, such as insulin-related, weight-related and/or cholesterol-related conditions in an animal subject.