172787-84-7Relevant articles and documents
A Mechanistically Designed Mono-cinchona Alkaloid Is An Excellent Catalyst for the Enantioselective Dihydroxylation of Olefins
Corey, E. J.,Noe, Mark C.,Grogan, Michael J.
, p. 6427 - 6430 (1994)
On the basis of ideas recently advanced regarding the origin of enantioselectivity in the OsO4 promoted dihydroxylation of olefins catalyzed by bis-cinchona alkaloid derivatives such as 1, specifically strong evidence for reaction via transition state assembly 2, the mono-quinidine derivative 3 was selected as a promising catalytic ligand.The experimental observation of high enantioselectivity promoted by 3 provides additional evidence in favor of transition-state 2.
