172791-01-4Relevant academic research and scientific papers
Synthesis and reactions of cyclopentadiene monoaziridine: A concise approach to the core of agelastatin A
Baron, Elise,O'Brien, Peter,Towers, Timothy D
, p. 723 - 726 (2002)
An improved protocol for the preparation of cyclopentadiene monoaziridine is described (88% yield). The utility of cyclopentadiene monoaziridine is demonstrated by its use in (i) the shortest synthetic entry into 4-amino substituted cyclopentenes and (ii)
Selective [2+1] aziridination of conjugated dienes with a nitridomanganese complex: A new route to alkenylaziridines
Nishimura,Minakata,Thongchant,Ryu,Komatsu
, p. 7089 - 7092 (2000)
Conjugated dienes were successfully aziridinated using a nitridomanganese complex as a nitrogen source. The reaction proceeded selectively and in good yield via [2+1] addition to give alkenylaziridines, with no evidence for the formation of any [4+1] addition products. The first asymmetric version of the reaction was revealed in the aziridination of diene 5 with chiral complex 1. (C) 2000 Elsevier Science Ltd.
