17280-90-9

Basic information

• Product Name: ethyl 2-oxo-1,3-benzoxazole-3(2H)-carboxylate
• Synonyms: 3(2H)-benzoxazolecarboxylic acid, 2-oxo-, ethyl ester
• CAS NO: 17280-90-9
• Molecular Formula: C₁₀H₉NO₄
• Molecular Weight: 207.1828
• Mol File: 17280-90-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 305.6°C at 760 mmHg
• Flash Point: 138.6°C
• Density: 1.369g/cm³
• Vapor Pressure: 0.000814mmHg at 25°C
• Refractive Index: 1.576
• CAS DataBase Reference: ethyl 2-oxo-1,3-benzoxazole-3(2H)-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-oxo-1,3-benzoxazole-3(2H)-carboxylate(17280-90-9)
• EPA Substance Registry System: ethyl 2-oxo-1,3-benzoxazole-3(2H)-carboxylate(17280-90-9)

Safety Data

• Hazardous Substances Data: 17280-90-9(Hazardous Substances Data)

Upstream product

• 56836-51-2 ethyl (2-hydroxyphenyl)carbamate 
• 627-11-2 2-Chloroethyl chloroformate 
• 17281-02-6 2-oxo-benzooxazole-3-carbonyl chloride 
• 64-17-5 ethanol 
• 59-49-4 2-Benzoxazolinone 
• 95-55-6 2-amino-phenol 
• 623-49-4 ethyl cyanoformate 
• 39123-50-7 (2-hydroxy-phenyl)-carbamic acid-(2-chloro-ethyl ester) 
• 541-41-3 chloroformic acid ethyl ester 

Downstream Products

• 56836-51-2 ethyl (2-hydroxyphenyl)carbamate 
• 59-49-4 2-Benzoxazolinone 

Relevant articles and documents

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Efficient and selective deprotection method for N-protected 2(3H)-benzoxazolones and 2(3H)-benzothiazolones

Cyclic carbamate flanked with heterocyclic or aliphatic moieties are frequently used in medicinal chemistry. The synthesis of derivatives bearing a free NH often requires the use of a protection method. A literature search reveals very few protection/deprotection methods for cyclic carbamates. In this paper, we described different methods applicable to 2(3H)-benzoxazolone and 2(3H)-benzothiazolone. Graphical abstract