17288-36-7

Basic information

• Product Name: 5-METHOXY-1H-PYRROLO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID
• Synonyms: 5-METHOXY-1H-PYRROLO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID;5-Methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid ,98%;5-Methoxy-6-azaindole-2-carboxylic acid;5-Methoxy-6-azaindole-3-carboxylic acid
• CAS NO: 17288-36-7
• Molecular Formula: C9H8N2O3
• Molecular Weight: 192.17
• Mol File: 17288-36-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 458.4 °C at 760 mmHg
• Flash Point: 231 °C
• Appearance: /
• Density: 1.459
• Vapor Pressure: 3.38E-09mmHg at 25°C
• Refractive Index: 1.688
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-METHOXY-1H-PYRROLO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHOXY-1H-PYRROLO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID(17288-36-7)
• EPA Substance Registry System: 5-METHOXY-1H-PYRROLO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID(17288-36-7)

Safety Data

• Statements: 20/21/22
• Safety Statements: 36/37
• Hazardous Substances Data: 17288-36-7(Hazardous Substances Data)

Usage

Chemical Properties

White to grey solid

InChI:InChI=1/C9H8N2O3/c1-14-8-3-5-2-6(9(12)13)11-7(5)4-10-8/h2-4,11H,1H3,(H,12,13)

Upstream product

• 3469-63-4 5-methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid ethyl ester 
• 3469-62-3 ethyl 3-(2-methoxy-5-nitropyridin-4-yl)-2-oxopropanoate 
• 6635-90-1 2-Methoxy-4-methyl-5-nitropyridine 

Downstream Products

• 1326283-49-1 5-methoxy-N-(2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1-methyl-1H-pyrrolo[2,3-c]pyridine-2-carboxamide 
• 1132610-92-4 methyl 5-methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylate 

Relevant articles and documents

Synthesis of the new ring system bispyrido[4',3':4,5]pyrrolo [1,2-a:1',2'-d]pyrazine and its deaza analogue

Derivatives of the new ring systems bispyrido[4',3':4,5]pyrrolo[1,2-a:1',2'-d] pyrazine-6,13-dione and its deaza analogue pyrido[4",3":4',5']pyrrolo-[1',2':4,5]pyrazino [1,2-a]indole-6,13-dione were conveniently synthesized through a four-step sequence. Symmetrical derivatives of the former ring system were obtained through self condensation. On the other hand, condensation of 6-azaindole carboxylic acid with indole 2-carboxylic acid afforded the deaza analogue ring system. Derivatives of the title ring system were tested by the National Cancer Institute (Bethesda, MD, USA) and four of them exhibited modest activity against MCF7 (a breast cancer cell line) and/or UO-31 (a renal cancer cell line).