172935-91-0

Usage

Uses

Used in Organic Synthesis:
2,6-Difluorobenzoyl hydrazine is used as a reagent in organic synthesis for the preparation of various pharmaceuticals and agrochemicals. Its unique structure and properties make it a valuable component in the development of new compounds with therapeutic and pesticidal potential.
Used in Pharmaceutical Industry:
2,6-Difluorobenzoyl hydrazine is used as a key intermediate in the synthesis of drugs with potential anti-tumor and anti-inflammatory properties. Its incorporation into drug molecules can enhance their therapeutic effects and provide new treatment options for various diseases.
Used in Agrochemical Industry:
2,6-Difluorobenzoyl hydrazine is used as a building block in the development of agrochemicals, such as pesticides and herbicides. Its unique structure can contribute to the creation of more effective and targeted agrochemicals, improving crop protection and yield.

Upstream product

• 19064-14-3 2,6-Difluorobenzoic acid,ethyl ester 
• 13671-00-6 methyl 2,6-difluorobenzoate 
• 385-00-2 2,6-difluorobenzoic acid 

Downstream Products

• 443797-96-4 4-[[5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-yl]amino]benzenesulfonamide 
• 929690-98-2 C₁₅H₁₀F₂N₂O₂ 
• 1310412-52-2 N-(2-butoxyethyl)-2,6-difluorobenzamide 
• 1310412-56-6 N-(2-tert-butoxyethyl)-2,6-difluorobenzamide 
• 1310412-63-5 N-[2-(tert-butyldimethylsilanyloxy)-2-phenylethyl]-2,6-difluorobenzamide 
• 1310412-44-2 1-(2,6-difluorobenzoylamino)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester 
• 1092277-13-8 5-(2,6-difluorophenyl)-1,3,4-oxadiazole-2-thione 

Relevant academic research and scientific papers

Synthesis and biological evaluation of novel resveratrol-oxadiazole hybrid heterocycles as potential antiproliferative agents

A novel class of resveratrol-oxadiazole hybrid compounds was synthesized to screen for their in vitro antiproliferative activity against three human cancer cell lines. All the compounds showed superior antiproliferative activity than the reference compound resveratrol. The most promising active compounds in this series were 1g, 2g, 1c, 2c, 2i and 1a (GI50 0.1 μM), endowed with excellent antiproliferative activity. Thus, we believe that resveratrol-oxadiazole hybrid compounds may possibly be used as a good leads for the development of new antiproliferative agents. Structures of newly synthesized compounds were confirmed by NMR and IR spectral data.

Synthesis and properties of iridium complexes based 1,3,4-oxadiazoles derivatives

A series of iridium complexes with 2,5-diaryl-[1,3,4]-oxadiazole ligands were synthesized and their electrochemical, photophysical, and electroluminescent (EL) properties studied. It was found that electron-withdrawing or donating substituents on the phenyl ring affected the emission maxima. Complex 3, iridium(III) bis(2,5-bis-(2-hydroxyphenyl)-[1,3,4]oxadiazolato-C2′,N3) (acetyl acetonate), was characterized by single-crystal X-ray structural determination. Three organic light emitting diodes devices were fabricated, which showed stable green-yellow luminescence.

Syntheses, antifeedant activity, and QSAR analysis of new Oxa(thia)diazolyl 3(2H)-pyridazinones

Twenty-eight new oxa(thia)diazolyl 3(2H)-pyridazinone derivatives were synthesized. Some compounds showed good chronic growth activities against the armyworm, Pseudaletia separata (Walker). Their EC50 values were determined in vivo. Nineteen 2-