172940-46-4

Upstream product

• 13386-35-1 2-methylamino-5-chlorobenzhydrol 
• 57-13-6 urea 
• 1022-13-5 5-chloro-2-(methylamino)benzophenone 

Downstream Products

• 26772-95-2 6-chloro-1-methyl-4-phenyl-3,4-dihydro-1H-quinazolin-2-one 

Relevant academic research and scientific papers

Ureas in Organic Synthesis. XII. Syntesis of 2-Amino-5-chlorobenzhydrylureas and Their Heterocyclization

A synthetic method was developed for hard-to-get biologically active 2-amino-5-chlorobenzhydrylureas based on reaction of the corresponding benzhydrols with urea in sulfuric acid. The 2-amino-5-chlorobenzhydrylureas were shown to easily undergo on heating cyclization to 1-R-1,2,3,4-tetrahydro-4-phenyl-chloroquinazolin-2-ones.