26772-95-2

Upstream product

• 80170-86-1 6-chloro-3,4-dihydro-1-methyl-4-phenyl-4-trichloromethyl-2(1H)-quinazolinone 
• 13386-35-1 2-methylamino-5-chlorobenzhydrol 
• 57-13-6 urea 
• 172940-46-4 N-(2-methylamino-5-chlorobenzhydryl)urea 
• 1022-13-5 5-chloro-2-(methylamino)benzophenone 
• 75-03-6 ethyl iodide 
• 26920-08-1 6-Chloro-1-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydroquinazoline 

Relevant academic research and scientific papers

Ureas in Organic Synthesis. XII. Syntesis of 2-Amino-5-chlorobenzhydrylureas and Their Heterocyclization

A synthetic method was developed for hard-to-get biologically active 2-amino-5-chlorobenzhydrylureas based on reaction of the corresponding benzhydrols with urea in sulfuric acid. The 2-amino-5-chlorobenzhydrylureas were shown to easily undergo on heating cyclization to 1-R-1,2,3,4-tetrahydro-4-phenyl-chloroquinazolin-2-ones.