172945-44-7

Basic information

• Product Name: Adenosine, 8-phenyl-, 2',3',5'-triacetate
• CAS NO: 172945-44-7
• Molecular Formula: C22H23N5O7
• Molecular Weight: 469.454
• Mol File: 172945-44-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Adenosine, 8-phenyl-, 2',3',5'-triacetate(CAS DataBase Reference)
• NIST Chemistry Reference: Adenosine, 8-phenyl-, 2',3',5'-triacetate(172945-44-7)
• EPA Substance Registry System: Adenosine, 8-phenyl-, 2',3',5'-triacetate(172945-44-7)

Safety Data

• Hazardous Substances Data: 172945-44-7(Hazardous Substances Data)

Upstream product

• 960-16-7 tributylphenylstannane 
• 31281-86-4 2',3',5'-tri-O-acetyl-8-bromoadenosine 
• 58-61-7 adenosine 
• 595-90-4 tetraphenyltin(IV) 
• 2946-39-6 8-bromoadenosine 
• 73340-78-0 8-Phenyladenosine 
• 108-24-7 acetic anhydride 
• 934-56-5 trimethyl(phenyl)stannane 

Downstream Products

• 833446-10-9 2',3',5'-tri-O-acetyl-1-[(2-methoxyethoxy)methyl]-8-phenylinosine 
• 833446-03-0 2',3',5'-tri-O-acetyl-8-phenylinosine 
• 73340-78-0 8-Phenyladenosine 

Relevant articles and documents

Selective Inhibition of Trypanosomal Glyceraldehyde-3-phosphate Dehydrogenase by Protein Structure-Based Design: Toward New Drugs for the Treatment of Sleeping Sickness

Within the framework of a project aimed at rational design of drugs against diseases caused by trypanosomes and related hemoflagellate parasites, selective inhibitors of trypanosomal glycolysis were designed, synthesized, and tested.The design was based u

Synthesis of novel 2-aryl AICAR derivatives

Novel 2-aryl AICAR (5-Amino-1-β-D-ribofuranosylimidazole-4- carboxamide) derivatives 8 were synthesized via the Suzuki-Miyaura cross-coupling reactions of 8-bromoadenosine. Following conversion of the adenine moiety of 4 to hypoxanthine (5) and the introduction of a MEM group, hydrolysis of 7 gave desired 2-aryl AICAR derivatives 8.