172988-64-6Relevant articles and documents
An Approach to Substituted 4-Hydroxypyran-2-ones
Ramirez, Mai-ly,Garey, Donna,Pena, Michael R.
, p. 1657 - 1660 (2007/10/03)
We examined a method for the preparation of 4-hydroxypyran-2-ones in two steps from aryl ketones and ethyl malonyl chloride (or ethyl 2-methylmalonyl chloride).These 4-hydroxypyran-2-ones are useful precursors as they may be transformed in two steps to the 2-methoxypyran-4-ones, which is found in phenoxan - a naturally occurring compound discovered to have anti-HIV activity.